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성인에서 장중첩증으로 발현된 과호산구 증후군 1예

Hypereosinophilic Syndrome Presenting as Intussusception in Adults

  • Chon, Nuri (Department of Internal Medicine, Hallym Hospital) ;
  • Kim, WooJung (Department of Internal Medicine, Hallym Hospital) ;
  • Park, Sang Young (Department of Internal Medicine, Hallym Hospital) ;
  • Kim, Kwang Hyun (Department of Internal Medicine, Hallym Hospital)
  • 투고 : 2014.02.19
  • 심사 : 2014.05.29
  • 발행 : 2014.11.01

초록

Hypereosinophilic syndrome (HES) is characterized by persistent eosinophilia associated with damage to multiple organs. Although the diagnostic criteria for HES include sustained hypereosinophilia for at least 6 months, early initiation of therapy may be recommended in patients exhibiting HES symptoms. Eosinophilic enteritis has been reported as a cause of intussusception in several cases. However, HES as a cause of intussusception has not yet been reported. In the present report, we describe a case of HES that manifested as jejunojejunal intussusception. Although long-standing hypereosinophilia was not confirmed, the patient required eosinophil-lowering therapy for an intestinal obstruction. The patient was treated with systemic corticosteroids, after which the symptoms and multiple organ involvement, including intussusception, improved dramatically, as noted on the radiological investigation. Moreover, surgery was not necessary.

키워드

참고문헌

  1. Shah AM, Joglekar M. Eosinophilic colitis as a complication of the hypereosinophilic syndrome. Postgrad Med J 1987;63:485-487. https://doi.org/10.1136/pgmj.63.740.485
  2. Jeon YW, Hong SJ, Kim HJ, et al. A hypereosinophilic syndrome presenting as eosinophilic colitis. Clin Endosc 2012;45:444-447. https://doi.org/10.5946/ce.2012.45.4.444
  3. Jung HK, Jung SA, Lee HC, Yi SY. A case of eosinophilic colitis as a complication of the hypereosinophilic syndrome. Korean J Gastrointest Endosc 1998;18:417-425.
  4. Marinis A, Yiallourou A, Samanides L, et al. Intussusception of the bowel in adults: a review. World J Gastroenterol 2009;15:407-411. https://doi.org/10.3748/wjg.15.407
  5. Begos DG, Sandor A, Modlin IM. The diagnosis and management of adult intussusception. Am J Surg 1997;173:88-94. https://doi.org/10.1016/S0002-9610(96)00419-9
  6. Kshirsagar AY, Jagtap SV, Kanojiya RP, Langade YB, Shinde SL, Shekhar N. Eosinophilic enteritis presenting as a rare cause for ileo-ileal intussusception. World J Gastroenterol 2007;13:6444-6445. https://doi.org/10.3748/wjg.v13.i47.6444
  7. Shin WG, Park CH, Lee YS, et al. Eosinophilic enteritis presenting as intussusception in adult. Korean J Intern Med 2007;22:13-17. https://doi.org/10.3904/kjim.2007.22.1.13
  8. Fauci AS, Harley JB, Roberts WC, et al. NIH conference. The idiopathic hypereosinophilic syndrome. Clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med 1982;97:78-92. https://doi.org/10.7326/0003-4819-97-1-78
  9. Tefferi A, Gotlib J, Pardanani A. Hypereosinophilic syndrome and clonal eosinophilia: point-of-care diagnostic algorithm and treatment update. Mayo Clin Proc 2010;85:158-164. https://doi.org/10.4065/mcp.2009.0503
  10. Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH. Eosinophilic gastroenteritis. Medicine (Baltimore) 1970;49:299-319. https://doi.org/10.1097/00005792-197007000-00003