Non-occlusive Mesenteric Ischemia (NOMI) Secondary to Traumatic Hemorrhagic Shock: Case Report

외상성 출혈성 쇼크 환자에서 발생한 비 폐쇄성 장간막 허혈

  • Lim, Kyoung Hoon (Trauma Center, Kyungpook National University Hospital) ;
  • Jung, Hee Kyung (Trauma Center, Kyungpook National University Hospital) ;
  • Cho, Jayun (Trauma Center, Kyungpook National University Hospital) ;
  • Lee, Sang Cjeol (Trauma Center, Kyungpook National University Hospital) ;
  • Park, Jinyoung (Trauma Center, Kyungpook National University Hospital)
  • 임경훈 (경북대학교병원 권역외상센터) ;
  • 정희경 (경북대학교병원 권역외상센터) ;
  • 조자윤 (경북대학교병원 권역외상센터) ;
  • 이상철 (경북대학교병원 권역외상센터) ;
  • 박진영 (경북대학교병원 권역외상센터)
  • Received : 2014.08.14
  • Accepted : 2014.09.03
  • Published : 2014.12.31

Abstract

Non-occlusive mesenteric ischemia (NOMI) encompasses all forms of mesenteric ischemia with patent mesenteric arteries. NOMI is commonly caused by decreased cardiac output resulting in hypoperfusion of peripheral mesenteric arteries. We report a case of NOMI secondary to hemorrhagic shock and rhabdomyolysis due to trauma. A 42-year-old man presented to our trauma center following a pedestrian trauma. On arrival, he was drowsy and in a state of hemorrhagic shock. He was found to have multiple fractures, both lung contusion and urethral rupture. An initial physical examination and abdominal computed tomography (CT) scan revealed no evidence of intra-abdominal injury. High doses of catecholamine were administered for initial 3 days due to unstable vital sign. On day 25 of hospitalization, follow-up abdominal CT scan demonstrated that short segment of small bowel loop was dilated and bowel wall was not enhanced. During exploratory laparotomy, necrosis of the terminal ileum with intact mesentery was detected and ileocecectomy was performed. His postoperative course was uneventful and is under rehabilitation.

Keywords

References

  1. Haglund U, Lundgren O. Non-occlusive acute intestinal vascular failure. Br J Surg 1979; 66: 155-8. https://doi.org/10.1002/bjs.1800660305
  2. Bassiouny HS. Nonocclusive mesenteric ischemia. Surg Clin North Am 1997; 77: 319-26. https://doi.org/10.1016/S0039-6109(05)70551-X
  3. Wilcox MG, Howard TJ, Plaskon LA, Unthank JL, Madura JA. Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia. Dig Dis Sci 1995; 40: 709-16. https://doi.org/10.1007/BF02064966
  4. Acosta S, Ogren M, Sternby NH, Bergqvist D, Bjorck M. Fatal nonocclusive mesenteric ischaemia: population-based incidence and risk factors. J Intern Med 2006; 259: 305-13. https://doi.org/10.1111/j.1365-2796.2006.01613.x
  5. Ludwig KA, Quebbeman EJ, Bergstein JM, Wallace JR, Wittmann DH, Aprahamian C. Shock-associated right colon ischemia and necrosis. J Trauma 1995; 39: 1171-4. https://doi.org/10.1097/00005373-199512000-00029
  6. Hirotada Kittaka MK, Yasuhiro Kitamura, Makiko Fukuda, Isao Nishihara, Yasuo Oishi, Hiroshi Akimoto. A case of nonocclusive mesenteric ischemia secondary to hemorrhagic shock due to trauma. JJAAM 2010; 21: 319-25.
  7. Brandt LJ, Boley SJ. Nonocclusive mesenteric ischemia. Annu Rev Med 1991; 42: 107-17. https://doi.org/10.1146/annurev.me.42.020191.000543
  8. Upponi S, Harvey JJ, Uberoi R, Ganeshan A. The role of radiology in the diagnosis and treatment of mesenteric ischaemia. Postgrad Med J 2013; 89: 165-72. https://doi.org/10.1136/postgradmedj-2012-131028
  9. Boley S, Frieber W, Winslow PR. Circulatory responses to acute reduction of superior mesenteric arterial flow. Physiologist 1969; 12: 180.
  10. Mitsuyoshi A, Obama K, Shinkura N, Ito T, Zaima M. Survival in nonocclusive mesenteric ischemia: early diagnosis by multidetector row computed tomography and early treatment with continuous intravenous high-dose prostaglandin E(1). Ann Surg 2007; 246: 229-35. https://doi.org/10.1097/01.sla.0000263157.59422.76
  11. Ward D, Vernava AM, Kaminski DL, Ure T, Peterson G, Garvin P, et al. Improved outcome by identification of high-risk nonocclusive mesenteric ischemia, aggressive reexploration, and delayed anastomosis. Am J Surg 1995; 170: 577-80. https://doi.org/10.1016/S0002-9610(99)80019-1