Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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The effect of Sargassum confusum on reduction of body fat in obese women

알쏭이모자반 (Sargassum confusum) 주정추출물이 성인여성 체지방 감소에 미치는 영향

  • Min, Ki Sung (Department of Food and Nutrition, Chungnam National University) ;
  • Han, Daeseok (Neo Food Resources Research Group, Korea Food Research Institute) ;
  • Kwon, Sang-Oh (R&D Center, S&D Co., Ltd.) ;
  • Yeo, Kyung-Mok (R&D Center, S&D Co., Ltd.) ;
  • Kim, Bok-Nam (Department of Tourism and Food Service Cuisine, Hallym Polytechnic University) ;
  • Ly, Sun Yung (Department of Food and Nutrition, Chungnam National University)
  • 민기성 (충남대학교 생활과학대학 식품영양학과) ;
  • 한 대석 (한국 식품 연구원 신소재 연구단) ;
  • 권상오 ((주)에스엔디 기업부설연구소) ;
  • 여경목 ((주)에스엔디 기업부설연구소) ;
  • 김복남 (한림성심대학 관광외식조리과) ;
  • 이선영 (충남대학교 생활과학대학 식품영양학과)
  • Received : 2013.10.01
  • Accepted : 2014.01.23
  • Published : 2014.02.28
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Abstract

Purpose: This study was conducted in order to investigate the effect of Sargassum confusum extracts on the reduction of body fat for eight weeks in overweight women ($BMI{\geq_-}23kg/m^2$). Methods: Subjects were classified by double-blind randomized trial as the control group (C group, n = 14) and the Sargassum confusum extract supplementation group (SC group, n = 16), which consumed 12 tablets per day. Questionnaires related to their health status were assessed twice (week 0 and week 8). Their dietary intake status was evaluated by 24-recall method and body compositions were measured using a bioelectrical impedance analyzer. In addition, we assessed the anti-obesity effect and the occurrence possibility of health risk factors during the supplementation periods by hematological and clinical analysis of blood. Results: Waist circumference and body fat (%) were significantly decreased in the SC group. Serum leptin level was also significantly decreased in the SC group. Defecation frequency was significantly increased in the SC group. The above results indicate that Sargassum confusum extract supplementation improves overweight on visceral fat and blood leptin level by increasing bowel movement. These results imply a decrease of health risk factors in overweight women. Seven subjects withdrew from the study due to adverse events; however, no differences regarding adverse events were observed between the control and treatment group. Conclusion: Therefore, Sargassum confusum extract is a plausible effective agent for body fat reduction in humans.

해조류인 알쏭이 모자반 추출물의 섭취로 인한 체지방 감소 효능을 평가하고자 이중맹검법을 사용하여 BMI 23 이상의 과체중 혹은 비만 성인 여성에게 8주간 알쏭이 모자반 추출물을 섭취하게 한 후 체격지수, 혈액 분석, 식사섭취상황 등을 조사하였다. 최종 대조군은 14명, 실험군은 16명이었으며 1일3회 각 4개의 캡슐을 섭취시켰다. 인체시험 결과 시험전후 비교시 대조군에 비하여 시험군의 체지방률과 체지방량, 허리둘레가 지속적으로 유의하게 감소하였으며 혈청 트리글리세롤과 렙틴농도가 더욱 유의하게 감소하였고 변배설량은 유의하게 증가하여 지방 배설효과를 기대할 수 있었다. 시험기간 동안 7명의 피험자가 심각하지 않은 부작용으로 시험에서 탈락하였으나 건강상 불편함을 호소하는 피험자 수의 두 군간의 차이는 보이지 않았다. 따라서 알쏭이 모자반 추출물은 8주간 섭취 시 심각한 부작용을 유발하지 않으면서 피험자의 허리둘레, 체지방율과 함께 혈청 렘틴 수치를 유의하게 감소시킬 수 있고 배변횟수를 유의하게 증가시켜 특히 복부비만을 해소할 수 있는 비교적 안전한 기능성 소재로 기대되므로 작용기전을 설명할 수 있는 심층 연구가 필요로 된다.

Keywords

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