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Lipiodol-induced pneumonitis following transarterial chemoembolization for ruptured hepatocellular carcinoma

파열 간암의 간동맥 항암 화학색전술 후 발생한 유도 폐렴

  • Kim, Haewon (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Yong Hoon (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Yoon, Hong Jin (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Lee, Kwang Hoon (Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Joo, Seung Moon (Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Byun, Min Kwang (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Lee, Jung Il (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Lee, Kwan Sik (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Ja Kyung (Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine)
  • 김혜원 (연세대학교 의과대학 내과학교실) ;
  • 김용훈 (연세대학교 의과대학 내과학교실) ;
  • 윤홍진 (연세대학교 의과대학 내과학교실) ;
  • 이광훈 (연세대학교 의과대학 영상의학교실) ;
  • 주승문 (연세대학교 의과대학 영상의학교실) ;
  • 변민광 (연세대학교 의과대학 내과학교실) ;
  • 이정일 (연세대학교 의과대학 내과학교실) ;
  • 이관식 (연세대학교 의과대학 내과학교실) ;
  • 김자경 (연세대학교 의과대학 내과학교실)
  • Received : 2013.08.10
  • Accepted : 2013.10.03
  • Published : 2014.12.31

Abstract

Transarterial chemoembolization (TACE) is a widely accepted nonsurgical modality used for the treatment of multinodular hepatocellular carcinoma (HCC). The careful selection of the candidate is important due to the risk of developing various side effects. Fever, nausea, abdominal pain, and liver enzyme elevation are commonly known side effects of TACE. Hepatic failure, ischemic cholecystitis, and cerebral embolism are also reported, although their incidence might be low. Pulmonary complication after TACE is rare, and the reported cases of lipiodol pneumonitis are even rarer. A 53-year-old man was treated with TACE for ruptured HCC associated with hepatitis B virus infection. On day 19 after the procedure, the patient complained of dyspnea and dry cough. Chest computed tomography showed diffuse ground glass opacities in the whole-lung fields, suggesting lipiodol-induced pneumonitis. After 2 weeks of conservative management, the clinical symptoms and radiologic abnormalities improved. Reported herein is the aforementioned case of lipiodol-induced pnemonitis after TACE, with literature review.

Keywords

Cited by

  1. Secondary adrenal insufficiency caused by sorafenib administration in a patient with hepatocellular carcinoma vol.33, pp.2, 2016, https://doi.org/10.12701/yujm.2016.33.2.155
  2. Lipiodol Pneumonitis Following Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma vol.20, pp.1, 2014, https://doi.org/10.17998/jlc.20.1.60