Journal of Yeungnam Medical Science
- Volume 31 Issue 2
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- Pages.82-88
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- 2014
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- 2799-8010(eISSN)
DOI QR Code
Weekly irinotecan and carboplatin for patients with small cell lung cancer
소세포 폐암 환자에서 이리노테칸, 카보플라틴 주별 분할 항암요법의 효과
- Lee, Hye-Won (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Jeong, Eu Gene (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Kim, Dong Hyun (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Lee, Hyuk (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Kang, Bo Hyoung (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Um, Soo-Jung (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Roh, Meesook (Department of Pathology, Dong-A University College of Medicine, Dong-A University Medical Center) ;
- Son, Choonhee (Division of Respiratory Medicine, Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Medical Center)
- 이혜원 (동아대학교 의과대학 내과학교실) ;
- 정유진 (동아대학교 의과대학 내과학교실) ;
- 김동현 (동아대학교 의과대학 내과학교실) ;
- 이혁 (동아대학교 의과대학 내과학교실) ;
- 강보형 (동아대학교 의과대학 내과학교실) ;
- 엄수정 (동아대학교 의과대학 내과학교실) ;
- 노미숙 (동아대학교 의과대학 병리학교실) ;
- 손춘희 (동아대학교 의과대학 내과학교실)
- Received : 2014.07.18
- Accepted : 2014.08.25
- Published : 2014.12.31
Abstract
Background: Lung cancer is the most common cause of cancer-related death worldwide and in Korea, and small cell lung cancer (SCLC) is the most deadly tumor type in the different lung cancer histology. Chemotherapy is the main strategy of the treatment for SCLC, and etoposide and platinum regimen has been the only standard chemotherapy for about 30 years. To test feasibility of weekly divided dose irinotecan and carboplatin for Korean patients is the aim of this study. Methods: Patients with histologically or cytologically confirmed extensive stage SCLC were included. Patients with limited stage (LD), who could not tolerate concurrent chemoradiotherapy were also included. All the patients received irinotecan