Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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The Use of Recombinant Human Bone Morphogenic Protein-2 (rhBMP-2) in Treatment for Cysts of the Oral and Maxillofacial Regions

  • Lee, Jong-Bum (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Kim, Taek-Woo (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Ryu, Seok-Hwan (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Shin, Dong-Yoon (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Ryu, Hyun-Ho (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Park, Seok-Yong (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Shin, Young-Cho (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Kim, Bok-Joo (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Hwang, Hee-Seong (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center) ;
  • Kim, Chul-Hoon (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center)
  • Received : 2013.07.29
  • Accepted : 2013.11.08
  • Published : 2014.01.30
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Abstract

The purpose of this study is to report on five cases treated with bone graft using recombinant human bone morphogenetic protein-2 (rhBMP-2) on jaw defects after cyst enucleation. We performed bone graft with BMP (rhBMP-2+${\beta}$-tricalcium phosphate/hydroxyapatite) wrapped with a collagen sponge on jaw defects after cyst enucleation. Postoperative panoramic radiographs were taken periodically. After 1 to 12 months, bone remodeling was observed in the jaw defect area. In our cases, there were few signs or symptoms of recurrence of the cyst during the follow-up period.

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References

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