Neurobiological Basis of Anxiety Related Disorders

불안 관련 장애의 신경생물학적 이해

  • Kim, Kyung-Min (Department of Psychiatry, CHA Bundang Medical Center, CHA University) ;
  • Kim, Min-Kyoung (Department of Psychiatry, CHA Bundang Medical Center, CHA University) ;
  • Lee, Sang-Hyuk (Department of Psychiatry, CHA Bundang Medical Center, CHA University)
  • 김경민 (차의과학대학교 분당차병원 정신건강의학교실) ;
  • 김민경 (차의과학대학교 분당차병원 정신건강의학교실) ;
  • 이상혁 (차의과학대학교 분당차병원 정신건강의학교실)
  • Received : 2014.08.04
  • Accepted : 2014.10.10
  • Published : 2014.11.30

Abstract

Anxiety disorders are characterized by dysregulation of neuroendocrine, neurotransmitter and neuroanatomical functions. Substantial advances in research method offered new insights into the neurobiologic mechanisms in anxiety disorders. Advances in molecular biology have enabled illumination of hormone and neurotransmitters that have important roles in anxiety. The neuroanatomic circuits related to anxiety are also being elucidated by improvements in neuroimaging technology such as structural and functional magnetic resonance imaging. This article reviews the research data in relation to the neurobiology underlying fear and pathologic anxiety and discusses their implications for development of biological treatments for anxiety disorders.

Keywords

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