Comparison of Prescription Patterns and Clinical Features according to Clinical Departments in Sedative-hypnotic Intoxication

진정수면제 중독 환자의 처방과에 따른 처방 및 임상양상 비교

  • Kim, Do Min (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Park, Won Bin (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Lim, Yong Su (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Kim, Jin Joo (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Jang, Jae Ho (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Jang, Jee Yong (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Yang, Hyuk Jun (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Lee, Geun (Department of Emergency Medicine, Gachon University Gil Medical Center)
  • 김도민 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 박원빈 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 임용수 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 김진주 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 장재호 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 장지용 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 양혁준 (가천대학교 의과대학 길병원 응급의학교실) ;
  • 이근 (가천대학교 의과대학 길병원 응급의학교실)
  • Received : 2014.08.11
  • Accepted : 2014.10.01
  • Published : 2014.12.31

Abstract

Purpose: The purpose of this study was to compare prescription patterns and clinical features according to clinical departments in sedative-hypnotic intoxication. Methods: This was a retrospective study of histories, substances of poisoning, acquisition routes, clinical courses, and outcomes of patients treated for acute intoxication in a single emergency medical center from January, 2011 to December, 2013. Results: A total of 769 patients were treated for acute intoxication, 281 patients ingested sedative hypnotics during the study period. Among 281 patients, 155 patients were prescribed by psychiatric department and 80 patients were prescribed by non-psychiatric department. Benzodiazepines were more likely to be prescribed by psychiatrists, and zolpidem was preferred by non-psychiatrists (p<0.001). Non-psychiatrists were more likely to prescribe short acting benzodiazepines than psychiatrists (p<0.001). However, there was no statistically significant difference in the clinical outcomes, including prevalence of admission to ICU, ventilator care, and length of stay in ICU. In patients prescribed by non-psychiatrists, there were more patients prescribed without psychiatric diagnosis and diagnosed as major depression disorder after hospitalization. Conclusion: To promote rational prescribing of sedative hypnotics, proper psychiatric evaluation should be performed before prescribing, and educational programs including the contents of interactions and side effects of sedative hypnotics are needed.

Keywords