DOI QR코드

DOI QR Code

Extracorporeal Worm Extraction of Diphyllobothrium nihonkaiense with Amidotrizoic Acid in a Child

  • Shin, Hye Kyung (Department of Pediatrics, Hanyang University College of Medicine) ;
  • Roh, Joo-Hyung (Department of Pediatrics, Hanyang University College of Medicine) ;
  • Oh, Jae-Won (Department of Pediatrics, Hanyang University College of Medicine) ;
  • Ryu, Jae-Sook (Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine) ;
  • Goo, Youn-Kyoung (Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine) ;
  • Chung, Dong-Il (Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine) ;
  • Kim, Yong Joo (Department of Pediatrics, Hanyang University College of Medicine)
  • Received : 2014.07.18
  • Accepted : 2014.09.10
  • Published : 2014.12.31

Abstract

Infection cases of diphyllobothriid tapeworms are not much in the below teen-age group. We report a case of Diphyllobothrium nihonkaiense infection in a 13-year-old boy. He presented with severe fatigue, occasional abdominal pain at night time. He also had several episodes of tapeworm segment discharge in his stools. By his past history, he had frequently eaten raw fish including salmon and trout with his families. Numerous eggs of diphyllobothriid tapeworm were detected in the fecal examination. We introduced amidotrizoic acid as a cathartic agent through nasogastroduodenal tube and let nearly whole length (4.75 m) of D. nihonkaiense be excreted through his anus. After a single dose of praziquantel, the child's stool showed no further eggs, and his symptoms disappeared. The evacuated worm was identified as D. nihonkaiense by mitochondrial cox1 gene analysis. Here we report a successful extracorporeal worm extraction from an infection case of D. nihonkaiense by the injection of amidotrizoic acid.

Keywords

References

  1. Yamane Y, Shiwaku K. Diphyllobothrium nihonkaiense and other marine-origin cestodes. Prog Med Parasitol Jpn 2003; 8: 245-254.
  2. Lee EB, Song JH, Park NS, Kang BK, Lee HS, Han YJ, Kim HJ, Shin EH, Chai JY. A case of Diphyllobothrium latum infection with a brief review of diphyllobothriasis in the Republic of Korea. Korean J Parasitol 2007; 45: 219-223. https://doi.org/10.3347/kjp.2007.45.3.219
  3. Jeon HK, Kim KH, Huh S, Chai JY, Min DY, Rim HJ, Eom KS. Morphologic and genetic identification of Diphyllobothrium nihonkaiense in Korea. Korean J Parasitol 2009; 47: 369-375. https://doi.org/10.3347/kjp.2009.47.4.369
  4. Park SH, Eom KS, Park MS, Kwon OK, Kim HS, Yoon JH. A case of Diphyllobothrium nihonkaiense infection as confirmed by mitochondrial COX1 gene sequence analysis. Korean J Parasitol 2013; 51: 471-473. https://doi.org/10.3347/kjp.2013.51.4.471
  5. Song SM, Yang HW, Jung MK, Heo J, Cho CM, Goo YK, Hong Y, Chung DI. Two human cases of Diphyllobothrium nihonkaiense infection in Korea. Korean J Parasitol 2014; 52: 197-199. https://doi.org/10.3347/kjp.2014.52.2.197
  6. Wicht B, de Marval F, Peduzzi R. Diphyllobothrium nihonkaiense (Yamane et al., 1986) in Switzerland: first molecular evidence and case reports. Parasitol Int 2007; 56: 195-199. https://doi.org/10.1016/j.parint.2007.02.002
  7. Kojima R, Ko T. Researches on intestinal parasites of Koreans in South Keisho-Do. Especially on the distribution of liver flukes. J Chosen Med Ass 1919; 26: 42-86 (in Japanese).
  8. Fujita A, Migita M, Ueda T, Fukunaga Y. A 2-year-old girl with Diphyllobothrium nihonkaiense infection treated with oral praziquantel and a laxative. J Nippon Med Sch 2008; 75: 225-227. https://doi.org/10.1272/jnms.75.225
  9. Yoshida M, Hasegawa H, Takaoka H, Miyata A. A case of Diphyllobothrium nihonkaiense infection successfully treated by oral administration of Gastrografin. Parasitol Int 1999; 48: 151-155. https://doi.org/10.1016/S1383-5769(99)00011-2
  10. Scholz T, Garcia HH, Kuchta R, Wicht B. Update on the human broad tapeworm (genus Diphyllobothrium), including clinical relevance. Clin Microbiol Rev 2009; 22: 146-160. https://doi.org/10.1128/CMR.00033-08
  11. Beaver PC, Jung RC, Cupp EW. Clinical Parasitology. 9th ed. Philadelphia, USA. Lea & Febiger. 1984, p 544-547.
  12. Yamane Y, Kamo H, Bylund G, Wikgren BJP. Diphyllobothrium nihonkaiense sp. nov. (Cestoda: Diphyllobothriidae): revised identification of Japanese broad tapeworm. Shimane J Med Sci 1986; 10: 29-48.
  13. Kim JH, Lee JH. Images in clinical medicine. Diphyllobothrium latum during colonoscopy. N Engl J Med 2010; 362: e40. https://doi.org/10.1056/NEJMicm0810335
  14. Park SC, Keum B, Jeen YT, Chun HJ. Diphyllobothrium latum accidentally detected by colonoscopy. Dig Liver Dis 2011; 43: 664. https://doi.org/10.1016/j.dld.2011.02.013
  15. Hirata M, Yamaguchi Y, Ikei Y, Koyama G, Matsui T, Ishida H, Takahashi S. A case of Diphyllobothrium latum/nihonkaiense infection identified by capsule endoscopy in small intestine. Gastrointest Endosc 2006; 64: 129-130. https://doi.org/10.1016/j.gie.2006.01.030
  16. Soga K, Sakagami J, Handa O, Konishi H, Wakabayashi N, Yagi N, Yamada M, Kokura S, Naito Y, Yoshikawa T, Arizono N. Long fish tapeworm in the intestine: an in situ observation by capsule endoscopy. Intern Med 2011; 50: 325-327. https://doi.org/10.2169/internalmedicine.50.4374
  17. Ko SB. Observation of deworming process in intestinal Diphyllobothrium latum parasitism by gastrografin injection into jejunum through double-balloon enteroscope. Am J Gastroenterol 2008; 103: 2149-2150. https://doi.org/10.1111/j.1572-0241.2008.01982_11.x
  18. Kim TH, Kim HK, Lee YS, Choi DH, Kang SH, Jeong SJ, Park TI, Kim IT. A case of Diphyllobothrium latum infection in a patient with abdominal pain. Korean J Gastroenterol 2007; 50: 384-387.