Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Clinical Features of Patients with Esophageal and Second Primary Cancers

  • Tsai, Huang-Wen (Department of General Surgery, Far Eastern Memorial Hospital) ;
  • Chang, Chih-Chun (Department of Clinical Pathology, Far Eastern Memorial Hospital) ;
  • Sun, Jen-Tang (Department of Emergency, Far Eastern Memorial Hospital) ;
  • Liou, Ching-Biau (Department of Clinical Pathology, Far Eastern Memorial Hospital) ;
  • Lin, Hsiu-Chen (Department of Clinical Pathology, Far Eastern Memorial Hospital) ;
  • Lin, I-Hsin (Department of Clinical Pathology, Far Eastern Memorial Hospital) ;
  • Yu, Yun-Chieh (Department of Clinical Pathology, Far Eastern Memorial Hospital) ;
  • Weng, Wei-Ling (Department of Clinical Pathology, Far Eastern Memorial Hospital) ;
  • Leong, Ka-I (Department of Chest Surgery, Far Eastern Memorial Hospital) ;
  • Yen, Tzung-Hai (Division of Nephrology and Clinical Toxicology, Chang Gung Memorial Hospital, Lin-Kou Medical Center) ;
  • Wu, Jiann-Ming (Department of General Surgery, Far Eastern Memorial Hospital)
  • Published : 2014.12.18
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Abstract

Background: The prevalence of esophageal cancer (EC) with second primary cancers (SPC) is increasing worldwide. This study was aimed to understand the clinical features of EC patients with SPC in the Taiwanese population. Materials and Methods: Clinical and laboratory data for 180 EC patients with or without SPC were collected between January 2009 and December 2013. Information on treatment approaches, location of SPCs and ABO blood type were also collected and stratified. Results: The most common SPC in EC patients was hypopharyngeal cancer, followed by laryngeal cancer and hepatocellular carcinoma in our study. Malignancies of colon, prostate and lung were also found. There was a significant higher portion of blood type A in the EC patients with SPC compared with those without (42.4% vs 19.5%, P=0.006). Conclusions: The frequency and SPC site distribution and blood type A should be considered in clinical evaluation of EC patients with a high risk of developing SPC in the Taiwanese population.

Keywords

References

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