DOI QR코드

DOI QR Code

한방치료와 화학·방사선요법을 병행하여 완전 관해된 진행성 위암 환자 1례

A Case Report of Complete Response of Advanced Gastric Carcinoma Patient Treated with Korean Medicine Treatment in Conjunction with Chemoradiation Therapy

  • 투고 : 2014.11.28
  • 심사 : 2014.12.20
  • 발행 : 2014.12.29

초록

Objectives : The purpose of this study is to report the effect of Korean Medicine Treatment (KMT) on the advanced gastric carcinoma (AGC) patient. Method : One advanced gastric carcinoma patient was treated by Korean Medicine Treatment composed of pharmacopuncture, acupuncture and herbal medicine. At the same time, he received chemotherapy (S-1 and Cisplatin) and radiotherapy. The effect of KMT was measured by scanning with Computed tomography (CT) and Esophagogastroduodenoscopy (EGD). Response was evaluated using the Response Evaluation Criteria in Solid Tumors (RECIST) Committee classification. Result : The tumor was disappeared after the treatment during 13 months (Complete Response (CR)). As treatment was performed, chemoradiation therapy induced complication was alleviated. Conclusion : This case provides us a possibility that Korean Medicine Treatment offers potential benefits for advanced gastric carcinoma patient.

키워드

참고문헌

  1. 국가 암 등록사업 연례보고서(2011년 암 등록통계). 한국중암암등록본부. 2013
  2. 박재갑, 박착일, 김노경. 종양학. p. 304. 서울, 일조각, 2003
  3. 하태경, 권성준. 진행성 위암환자에 있어 TS-1 또는 TS-1/CDDP의 항암효과 및 안정성. 대한위암학회지. 6(3):139-145, 2006
  4. Bang YJ, Cutsem EV, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, Aprile G, Kulikov E, Hill J, Lehle M, Ruschoff J, Kang YK. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 376(9742):687-697, 2010 https://doi.org/10.1016/S0140-6736(10)61121-X
  5. Park JS, Yoo HS, Lee YW, Cho JH, Son CG, Cho CK. Wheel balance cancer therapy in the treatment of metastatic gastric carcinoma : a retrospective analysis of 62 patients. Korean J. Oriental Int. Med. 28(3):531-543, 2007
  6. Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, Rubinstein L, Shankar L, Dodd L, Kaplan R, Lacombe D, Verweij J. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 45(2):228-247, 2008
  7. National Cancer Information Center. Available from: http://www.cancer.go.kr
  8. 서영철, 임성우, 이원철. 胃癌의 處方 運用 및 化學療法 竝行 治療에 關한 小考. 대한암한의학회지. 3(1):193-206, 1997
  9. Wu B, Zhou RX, Chen MJ, Zhang YL, Qu Y, Zhou MS, Gong QM, Chen P, Zhao BR, Li WY. Effect of acupuncture on immunomodulation in patients with malignant tumors. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2(4):266-269, 1996
  10. 최정은, 조종관, 이연월, 유화승. 암 치료에서의 침술의 가치. 대한암한의학회지. 15(1):1-17, 2010
  11. 장성봉. 산양산삼의 항암효능 규명을 위한 유전자 분석. 박사학위논문. 상지대학교. 2008
  12. Kwon KR, Park CW, Ra MS, Cho CK. Clinical observation of multiple metastatic cancer patient with hepatocellular carcinoma treated with cultivated wild ginseng herbal acupuncture therapy. The Journal of Korean Acupuncture & Moxibustion Society. 22(2):211-217, 2005
  13. 김구, 최용석, 주종천, 문구. 산양산삼 약침치료로 종양 퇴축을 보인 폐암환자에 대한 증례보고. 대한약침학회지. 14(4):33-37, 2011 https://doi.org/10.3831/KPI.2011.14.4.033
  14. Joo SS, Won TJ, Kim MS, Lee DI. Hematopoietic effect of ginsenoside Rg3 in ICR mouse primary cultures and its application to a biological response modifier. Fitoterapia. 75(3):337-341, 2004 https://doi.org/10.1016/j.fitote.2004.02.008
  15. Kim BJ, Nah SY, Jeon JH, So IS, Kim SJ. Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells. Basic Clin Pharmacol Toxicol. 109:233-239, 2011 https://doi.org/10.1111/j.1742-7843.2011.00706.x
  16. Chen ZJ, Cheng J, Huang YP, Han SL, Liu NX, Zhu GB, Yao JG. Effect of adjuvant chemotherapy of ginsenoside Rg3 combined with mitomycin C and tegafur in advanced gastric cancer. Zhonghua Wei Chang Wai Ke Za Zhi. 10(1):64-66, 2007
  17. Bang JY, Kim EY, Shim TK, Yoo HS, Lee YW, Kim YS, Cho CK, Choi YJ, Jeong HJ, Kang IC. Analysis of anti-angiogenic mechanism of HangAmDan-B(HAD-B), a Korean traditional medicine, using antibody microarray chip. Biochip J. 4(4):350-355, 2010 https://doi.org/10.1007/s13206-010-4412-5
  18. 박재우, 유화승, 조종관, 이연월. 항암플러스 투여 후 호전된 진행성 위암 환자 증례보고. 대전대학교 한의학 연구소 논문집. 19(2):153-158, 2011
  19. Park JW, Yoon JW, Cho CK, Lee YW, Yoo HS. Prospective Analysis on survival outcomes of stage IV metastatic gastric cancer patients treated with HangAm-Plus. China J Integr Med. 20(1):49-55, 2014 https://doi.org/10.1007/s11655-012-1084-0