Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
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Comprehensive Review of Endotoxin Level Reported in Metalworking Operations

금속 가공유 취급 공정에서 엔도톡신 발생 및 노출 특성 고찰

  • Park, Dong-Uk (Department of Environmental Health, Korea National Open University)
  • 박동욱 (한국방송통신대학교 환경보건학과)
  • Received : 2014.12.05
  • Accepted : 2014.12.21
  • Published : 2014.12.31
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Abstract

Objectives: The aim of this study is to comprehensively summarize endotoxin levels reported in operations using metalworking fluids(MWFs). Methods: An extensive literature review was conducted of studies reporting endotoxin levels in processes using metalworking fluids. Keyword search terms included 'metalworking fluids', 'machining fluids', 'metalworking operation', 'machining operation' and 'endotoxin', which were used in combination. Results: A total of ten manuscripts were found to report on airborne endotoxin levels from metalworking operations in the automobile industry. Polycarbonate(PC), polyvinyl chloride(PVC) and mixed cellulose ester(MCE) were used to collect airborne endotoxin. Limulus Amebocyte Lysate was mainly used to quantify endotoxin amount. The levels of airborne endotoxin reviewed varied considerably, ranging from < $4EU/m^3$ to $790EU/m^3$, which was found to be far lower than those from cotton and potato processing plants, sawmills, and poultry farms. Several studies assumed that exposure to endotoxin could be a causative agent of respiratory diseases. Conclusions: Inhalation endotoxin exposure levels reported from metalworking operations were found to be lower than those from industries handling organic materials, even though it could be considered as a possible cause for several respiratory diseases.

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