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Primitive neuroectodermal tumor of the maxillary sinus in an elderly male: A case report and literature review

  • Shah, Saiquat (Department of Dental Public Health, Bangladesh Dental College) ;
  • Huh, Kyung-Hoe (Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Yi, Won-Jin (Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Heo, Min-Suk (Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Lee, Sam-Sun (Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Choi, Soon-Chul (Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University)
  • 투고 : 2013.09.24
  • 심사 : 2014.07.22
  • 발행 : 2014.12.31

초록

Primitive neuroectodermal tumor (PNET), which belongs to the Ewing's sarcoma (ES) family of tumors, is mainly seen in children and young adults. PNETs are extremely rare in the maxilla. Here, we report a case of PNET of the left maxillary sinus in an elderly male. Magnetic resonance imaging (MRI) revealed a slightly enhanced solid mass occupying the left maxillary sinus and infiltrating into the retroantral space. A partial maxillectomy was performed. Despite postoperative chemotherapy, follow-up computed tomography (CT) and MRI revealed a nodal metastasis in the submandibular space. Neck dissection was performed. However, the patient died 10 months after the second surgery because of distant metastasis to the liver. MRI and CT were particularly useful in detecting the extent of the tumor, recurrence, and metastasis. Further, a literature review of the previously reported PNET cases of the maxilla was carried out. In this paper, we also discuss the current approach for the diagnosis and management of these tumors.

키워드

참고문헌

  1. Windfuhr JP. Primitive neuroectodermal tumor of the head and neck: incidence, diagnosis, and management. Ann Otol Rhinol Laryngol 2004; 113: 533-43. https://doi.org/10.1177/000348940411300705
  2. Nikitakis NG, Salama AR, O'Malley BW Jr, Ord RA, Papadimitriou JC. Malignant peripheral primitive neuroectodermal tumor-peripheral neuroepithelioma of the head and neck: a clinicopathologic study of five cases and review of the literature. Head Neck 2003; 25: 488-98. https://doi.org/10.1002/hed.10260
  3. Schmidt D, Herrmann C, Jurgens H, Harms D. Malignant peripheral neuroectodermal tumor and its necessary distinction from Ewing's sarcoma. A report from the Kiel Pediatric Tumor Registry. Cancer 1991; 68: 2251-9. https://doi.org/10.1002/1097-0142(19911115)68:10<2251::AID-CNCR2820681025>3.0.CO;2-X
  4. Jurgens H, Bier V, Harms D, Beck J, Brandeis W, Etspuler G, et al. Malignant peripheral neuroectodermal tumors. A retrospective analysis of 42 patients. Cancer 1988; 61: 349-57. https://doi.org/10.1002/1097-0142(19880115)61:2<349::AID-CNCR2820610226>3.0.CO;2-0
  5. Hart MN, Earle KM. Primitive neuroectodermal tumors of the brain in children. Cancer 1973; 32: 890-7. https://doi.org/10.1002/1097-0142(197310)32:4<890::AID-CNCR2820320421>3.0.CO;2-O
  6. Dehner LP. Peripheral and central primitive neuroectodermal tumors. A nosologic concept seeking a consensus. Arch Pathol Lab Med 1986; 110: 997-1005.
  7. Batsakis JG, Mackay B, el-Naggar AK. Ewing's sarcoma and peripheral primitive neuroectodermal tumor: an interim report. Ann Otol Rhinol Laryngol 1996; 105: 838-43. https://doi.org/10.1177/000348949610501014
  8. Mohindra P, Zade B, Basu A, Patil N, Viswanathan S, Bakshi A, et al. Primary PNET of maxilla: an unusual presentation. J Pediatr Hematol Oncol 2008; 30: 474-7. https://doi.org/10.1097/MPH.0b013e31816e2309
  9. Khoury JD. Ewing sarcoma family of tumors. Adv Anat Pathol 2005; 12: 212-20. https://doi.org/10.1097/01.pap.0000175114.55541.52
  10. Alobid I, Bernal-Sprekelsen M, Alos L, Benitez P, Traserra J, Mullol J. Peripheral primitive neuroectodermal tumour of the left maxillary sinus. Acta Otolaryngol 2003; 123: 776-8. https://doi.org/10.1080/00016480310001213
  11. Jones JE, McGill T. Peripheral primitive neuroectodermal tumors of the head and neck. Arch Otolaryngol Head Neck Surg 1995; 121: 1392-5. https://doi.org/10.1001/archotol.1995.01890120050009
  12. Marina NM, Etcubanas E, Parham DM, Bowman LC, Green A. Peripheral primitive neuroectodermal tumor (peripheral neuroepithelioma) in children. A review of the St. Jude experience and controversies in diagnosis and management. Cancer 1989; 64: 1952-60. https://doi.org/10.1002/1097-0142(19891101)64:9<1952::AID-CNCR2820640931>3.0.CO;2-W
  13. Kushner BH, Hajdu SI, Gulati SC, Erlandson RA, Exelby PR, Lieberman PH. Extracranial primitive neuroectodermal tumors. The Memorial Sloan-Kettering Cancer Center experience. Cancer 1991; 67: 1825-9. https://doi.org/10.1002/1097-0142(19910401)67:7<1825::AID-CNCR2820670702>3.0.CO;2-3
  14. Slootweg PJ, Straks W, Noorman van der Dussen MF. Primitive neuroectodermal tumour of the maxilla. Light microscopy and ultrastructural observations. J Maxillofac Surg 1983; 11: 54-7. https://doi.org/10.1016/S0301-0503(83)80016-2
  15. Filiatrault D, Jequier S, Brochu P. Pediatric case of the day. Primitive neuroectodermal tumor (PNET) of the right maxillary sinus. Radiographics 1993; 13: 1397-9. https://doi.org/10.1148/radiographics.13.6.8290733
  16. Shah N, Roychoudhury A, Sarkar C. Primitive neuroectodermal tumor of maxilla in an adult. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995; 80: 683-6. https://doi.org/10.1016/S1079-2104(05)80252-5
  17. Ibarburen C, Haberman JJ, Zerhouni EA. Peripheral primitive neuroectodermal tumors. CT and MRI evaluation. Eur J Radiol 1996; 21: 225-32. https://doi.org/10.1016/0720-048X(95)00731-5
  18. Kao SY, Yang J, Yang AH, Chang KW, Chang RC. Peripheral primitive neuroectodermal tumor of the maxillary gingivae with metastasis to cervical lymph nodes: report of a case. J Oral Maxillofac Surg 2002; 60: 821-5. https://doi.org/10.1053/joms.2002.33253
  19. Sun G, Li Z, Li J, Wang C. Peripheral primitive neuroectodermal tumour of the maxilla. Br J Oral Maxillofacial Surg 2007; 45: 226-7. https://doi.org/10.1016/j.bjoms.2005.07.028
  20. Kimber C, Michalski A, Spitz L, Pierro A. Primitive neuroectodermal tumours: anatomic location, extent of surgery, and outcome. J Pediatr Surg 1998; 33: 39-41. https://doi.org/10.1016/S0022-3468(98)90357-8
  21. Rivera-Luna R, Gomez-Martinez R, Leal-Leal C, Cardenas-e ancillary chemotherapy approach of any value in the treatment of infratentorial primitive neuroectodermal tumors with surgery and radiotherapy? Childs Nerv Syst 1998; 14: 109-13. https://doi.org/10.1007/s003810050189
  22. Zimmermann T, Blutters-Sawatzki R, Flechsenhar K, Padberg WM. Peripheral primitive neuroectodermal tumor: challenge for multimodal treatment. World J Surg 2001; 25: 1367-72.
  23. Mendel E, Levy ML, Raffel C, McComb JG, Pikus H, Nelson MD Jr, et al. Surveillance imaging in children with primitive neuroectodermal tumors. Neurosurgery 1996: 38: 692-5. https://doi.org/10.1227/00006123-199604000-00011

피인용 문헌

  1. Computed Tomography and Magnetic Resonance Imaging Characteristics of Peripheral Primitive Neuroectodermal Tumor: A Retrospective Analysis of 16 Cases vol.41, pp.2, 2014, https://doi.org/10.1097/rct.0000000000000496