한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)

  • 제29권4호
  • /
  • Pages.370-375
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  • 2014
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  • 1229-1153(pISSN)
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  • 2465-9223(eISSN)
한국식품위생안전성학회 (The Korean Society of Food Hygiene and Safety)
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큰실말에서 분리된 식이섬유가 고지방식이로 유도된 흰쥐의 콜레스테롤에 미치는 영향

Effects of Cladosiphon Okamuranus Dietary Fiber on Cholesterol in High Fat Diet-Fed Rats

  • 배귀정 (신라대학교 의생명과학대학 생명공학과) ;
  • 손정현 (신라대학교 의생명과학대학 생명공학과) ;
  • 이재화 (신라대학교 의생명과학대학 생명공학과) ;
  • 정남옥 ;
  • 하배진 (신라대학교 의생명과학대학 생명공학과)
  • Bae, Gui-Jeong (Department of Biotechnology, College of Medical Life Science, Silla University) ;
  • Son, Jeong-Hyeon (Department of Biotechnology, College of Medical Life Science, Silla University) ;
  • Lee, Jae-Hwa (Department of Biotechnology, College of Medical Life Science, Silla University) ;
  • Jeong, Nam-Ock (MS Global Bio Co., Ltd.) ;
  • Ha, Bae-Jin (Department of Biotechnology, College of Medical Life Science, Silla University)
  • 투고 : 2014.08.21
  • 심사 : 2014.10.24
  • 발행 : 2014.12.31
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초록

Cladosiphon okamuranus is edible brown algae cultured commercially and massively at Okinawa coast. Dietary fiber occupying most of C. okamuranus isn't digested and absorbed by digestive enzymes of human. But it is known to prevent and treat constipation as metabolic disease. This study was to investigate the effects of dietary fiber extracted from C. okamuranus on the damage of liver and the blood cholesterol level in the high fat diet-fed rats. The effects were measured by the levels of aspartate aminotransferase (ALT), alanine aminotransferase (AST), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) in sera. The levels of ALT, AST, TC, TG and LDL were significantly reduced in the C. okamuranus-treated group compared with the high fat diet group. But HDL level was markedly increased. The results showed that the dietary fiber extracts from C. okamuranus have the inhibitive effects of cholesterol biosynthesis in the high fat diet-fed rats.

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