DOI QR코드

DOI QR Code

How to Achieve Complete and Permanent Pulmonary Vein Isolation without Complications

  • Han, Seongwook (Central Utah Clinic-Cardiology, Utah Valley Regional Medical Center) ;
  • Hwang, Chun (Central Utah Clinic-Cardiology, Utah Valley Regional Medical Center)
  • Published : 2014.05.30

Abstract

The efficacy and safety of catheter ablation for the management of atrial fibrillation (AF) has been improved in recent years. Radiofrequency (RF) catheter ablation for maintaining sinus rhythm is superior to the current antiarrhythmic drug therapy in selected patients. Pulmonary vein isolation (PVI) is the cornerstone of various catheter ablation strategies. It is well recognized that pulmonary vein (PV) antrum contributes to the AF initiation and/or perpetuation. Since PV stenosis is a complication of ablation within a PV, the ablation site for PVI has shifted to the junction between the left atrium and the PV rather than the ostium of the PV. However, PV reconnection after ablation is the major cause of recurrence of AF. The recovery of PV conduction could be caused by anatomical variations such as the failure to produce complete transmural lesion or gaps at the ablation line due to the transient electrophysiologic effects from the RF ablation. In this review, we discussed several factors to be considered for the achievement of the best PVI, including clinical aspects and technical aspects.

Keywords

References

  1. Calkins H, Kuck KH, Cappato R, et al. 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design: a report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation. Developed in partnership with the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC) and the European Cardiac Arrhythmia Society (ECAS); and in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), and the Society of Thoracic Surgeons (STS). Endorsed by the governing bodies of the American College of Cardiology Foundation, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, the Asia Pacific Heart Rhythm Society, and the Heart Rhythm Society. Heart Rhythm 2012;9:632-96. https://doi.org/10.1016/j.hrthm.2011.12.016
  2. Calkins H, Reynolds MR, Spector P, et al. Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses. Circ Arrhythm Electrophysiol 2009;2:349-61. https://doi.org/10.1161/CIRCEP.108.824789
  3. Piccini JP, Lopes RD, Kong MH, Hasselblad V, Jackson K, Al-Khatib SM. Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials. Circ Arrhythm Electrophysiol 2009;2:626-33. https://doi.org/10.1161/CIRCEP.109.856633
  4. Parkash R, Tang AS, Sapp JL, Wells G. Approach to the catheter ablation technique of paroxysmal and persistent atrial fibrillation: a meta-analysis of the randomized controlled trials. J Cardiovasc Electrophysiol 2011;22:729-38. https://doi.org/10.1111/j.1540-8167.2011.02010.x
  5. Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 1998;339:659-66. https://doi.org/10.1056/NEJM199809033391003
  6. Haissaguerre M, Jais P, Shah DC, et al. Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci. Circulation 2000;101:1409-17. https://doi.org/10.1161/01.CIR.101.12.1409
  7. Kalifa J, Jalife J, Zaitsev AV, et al. Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation. Circulation 2003;108:668-71. https://doi.org/10.1161/01.CIR.0000086979.39843.7B
  8. Kumagai K, Ogawa M, Noguchi H, Yasuda T, Nakashima H, Saku K. Electrophysiologic properties of pulmonary veins assessed using a multielectrode basket catheter. J Am Coll Cardiol 2004;43:2281-9. https://doi.org/10.1016/j.jacc.2004.01.051
  9. Sanders P, Berenfeld O, Hocini M, et al. Spectral analysis identifies sites of high-frequency activity maintaining atrial fibrillation in humans. Circulation 2005;112:789-97. https://doi.org/10.1161/CIRCULATIONAHA.104.517011
  10. Lin YJ, Tsao HM, Chang SL, et al. Role of high dominant frequency sites in nonparoxysmal atrial fibrillation patients: insights from high-density frequency and fractionation mapping. Heart Rhythm 2010;7:1255-62. https://doi.org/10.1016/j.hrthm.2010.06.019
  11. Cappato R, Calkins H, Chen SA, et al. Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circ Arrhythm Electrophysiol 2010;3:32-8. https://doi.org/10.1161/CIRCEP.109.859116
  12. Arbelo E, Brugada J, Hindricks G, et al. ESC-EURObservational Research Programme: the Atrial Fibrillation Ablation Pilot Study, conducted by the European Heart Rhythm Association. Europace 2012;14:1094-103. https://doi.org/10.1093/europace/eus153
  13. Hassink RJ, Aretz HT, Ruskin J, Keane D. Morphology of atrial myocardium in human pulmonary veins: a postmortem analysis in patients with and without atrial fibrillation. J Am Coll Cardiol 2003;42:1108-14. https://doi.org/10.1016/S0735-1097(03)00918-5
  14. Saito T, Waki K, Becker AE. Left atrial myocardial extension onto pulmonary veins in humans: anatomic observations relevant for atrial arrhythmias. J Cardiovasc Electrophysiol 2000;11:888-94. https://doi.org/10.1111/j.1540-8167.2000.tb00068.x
  15. Tan AY, Li H, Wachsmann-Hogiu S, Chen LS, Chen PS, Fishbein MC. Autonomic innervation and segmental muscular disconnections at the human pulmonary vein-atrial junction: implications for catheter ablation of atrial-pulmonary vein junction. J Am Coll Cardiol 2006;48:132-43. https://doi.org/10.1016/j.jacc.2006.02.054
  16. McGann CJ, Kholmovski EG, Oakes RS, et al. New magnetic resonance imaging-based method for defining the extent of left atrial wall injury after the ablation of atrial fibrillation. J Am Coll Cardiol 2008;52: 1263-71. https://doi.org/10.1016/j.jacc.2008.05.062
  17. Kowalski M, Grimes MM, Perez FJ, et al. Histopathologic characterization of chronic radiofrequency ablation lesions for pulmonary vein isolation. J Am Coll Cardiol 2012;59:930-8. https://doi.org/10.1016/j.jacc.2011.09.076
  18. Ranjan R, Kato R, Zviman MM, et al. Gaps in the ablation line as a potential cause of recovery from electrical isolation and their visualization using MRI. Circ Arrhythm Electrophysiol 2011;4:279-86. https://doi.org/10.1161/CIRCEP.110.960567
  19. Wittkampf FH, Hauer RN, Robles de Medina EO. Control of radiofrequency lesion size by power regulation. Circulation 1989;80:962-8. https://doi.org/10.1161/01.CIR.80.4.962
  20. Jain MK, Wolf PD. Temperature-controlled and constant-power radiofrequency ablation: what affects lesion growth? IEEE Trans Biomed Eng 1999;46:1405-12. https://doi.org/10.1109/10.804568
  21. Kautzner J, Neuzil P, Peichl P, et al. Contact force, force time integral and lesion continuity are critical to improve durable PV isolation: EFFICAS II results. Heart Rhythm 2012;9:S28.
  22. Cabrera JA, Ho SY, Climent V, Fuertes B, Murillo M, Sanchez-Quintana D. Morphological evidence of muscular connections between contiguous pulmonary venous orifices: relevance of the interpulmonary isthmus for catheter ablation in atrial fibrillation. Heart Rhythm 2009;6: 1192-8. https://doi.org/10.1016/j.hrthm.2009.04.016
  23. Andrade JG, Pollak SJ, Monir G, et al. Pulmonary vein isolation using a pace-capture-guided versus an adenosine-guided approach: effect on dormant conduction and long-term freedom from recurrent atrial fibrillation-- a prospective study. Circ Arrhythm Electrophysiol 2013;6: 1103-8. https://doi.org/10.1161/CIRCEP.113.000454
  24. Sotomi Y, Inoue K, Ito N, et al. Cause of very late recurrence of atrial fibrillation or flutter after catheter ablation for atrial fibrillation. Am J Cardiol 2013;111:552-6. https://doi.org/10.1016/j.amjcard.2012.10.040

Cited by

  1. High density mapping guided partial antral ablation for a pulmonary vein isolation vol.11, pp.1, 2014, https://doi.org/10.1038/s41598-021-96004-4