Tuberculosis and Respiratory Diseases

  • 제77권5호
  • /
  • Pages.223-226
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  • 2014
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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Aspergillus Tracheobronchitis in a Mild Immunocompromised Host

  • Cho, Byung Ha (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Oh, Youngmin (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Kang, Eun Seok (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Hong, Yong Joo (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Jeong, Hye Won (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Lee, Ok-Jun (Department of Pathology, Chungbuk National University College of Medicine) ;
  • Chang, You-Jin (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Choe, Kang Hyeon (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Lee, Ki Man (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • An, Jin-Young (Department of Internal Medicine, Chungbuk National University College of Medicine)
  • 투고 : 2014.07.14
  • 심사 : 2014.08.18
  • 발행 : 2014.11.28
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초록

Aspergillus tracheobronchitis is a form of invasive pulmonary aspergillosis in which the Aspergillus infection is limited predominantly to the tracheobronchial tree. It occurs primarily in severely immunocompromised patients such as lung transplant recipients. Here, we report a case of Aspergillus tracheobronchitis in a 42-year-old man with diabetes mellitus, who presented with intractable cough, lack of expectoration of sputum, and chest discomfort. The patient did not respond to conventional treatment with antibiotics and antitussive agents, and he underwent bronchoscopy that showed multiple, discrete, gelatinous whitish plaques mainly involving the trachea and the left bronchus. On the basis of the bronchoscopic and microbiologic findings, we made the diagnosis of Aspergillus tracheobronchitis and initiated antifungal therapy. He showed gradual improvement in his symptoms and continued taking oral itraconazole for 6 months. Physicians should consider Aspergillus tracheobronchitis as a probable diagnosis in immunocompromised patients presenting with atypical respiratory symptoms and should try to establish a prompt diagnosis.

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참고문헌

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피인용 문헌

  1. Death due to Aspergillus Tracheobronchitis: An Autopsy Case vol.42, pp.4, 2018, https://doi.org/10.7580/kjlm.2018.42.4.164
  2. Differences in Clinical Characteristics of Invasive Tracheobronchial Aspergillosis according to the Presence of Invasive Pulmonary Aspergillosis vol.84, pp.4, 2014, https://doi.org/10.4046/trd.2021.0029