A Case of Mandible Osteomyelitis Mimicking Recurrent Tongue Cancer

재발성 설암으로 오인된 하악골 골수염 1예

  • Park, Sangheon (Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Jung, Kwangjin (Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Park, Min Woo (Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Jung, Kwang-Yoon (Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine)
  • 박상헌 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정광진 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 박민우 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정광윤 (고려대학교 의과대학 이비인후-두경부외과학교실)
  • Received : 2013.08.01
  • Accepted : 2013.09.27
  • Published : 2013.11.30

Abstract

Osteomyelitis is an infection of bone or bone marrow, caused by pyogenic bacteria or mycobacterium. Osteomyelitis can be acute or chronic, inflammatory process of the bone and its structures. Chronic osteomyelitis will result in variable sclerosis and deformity of the affected bone. With an infection of the bone, the subsequent inflammatory response will elevate this overlying periosteum, leading to a loss of the nourishing vasculature, vascular thrombosis, and bone necrosis, resulting occasionally in formation of sequestra. These become areas that are more resistant to systemic antibiotic therapy due to lack of the normal Havesian canals that are blocked by scar tissue. At this aspect, not only systemic antibiotic therapy, but also surgical debridement maybe required to remove the affected bone and prevent disease propagation to adjacent areas. We experienced a patient who diagnosed tongue cancer and underwent wide partial glossectomy few years before, with an ulcerative lesion around right retromolar trigon. We diagnosed cancer recurrence because PET indicated hot uptake on mandible which was nearby previous tongue tumor site. The patient received hemiglossectomy via paramedian mandibulotomy, partial mandibulectomy and fibula osteocutaneous free flap reconstruction. But final diagnosis was mandible osteomyelitis on pathology report. Here, we present the case with a review of the related literatures.

Keywords

References

  1. Mallikarjun K, Kohli A, Arvind K, Vatsala V, Bhayya DP, Shyagali TR. Chronic suppurative osteomyelitis of the mandible. J Int Oral Health 2011;3:57-62.
  2. Marx RE. Chronic osteomyelitis of the jaws. Oral and maxillofacial surgery clinics of North America. Philadelphia: Saunders; 1992. p.367-438.
  3. Choi JU, Lee JK, Oh SE, Lee DW. Submandibular cutaneous draining sinus tract from mandibular osteomyelitis. Korean J Otorhinolaryngol-Head Neck Surg. 2009;52:549-551. https://doi.org/10.3342/kjorl-hns.2009.52.6.549
  4. Ducic Y. Osteomyelitis of the mandible. Southern Medical J. 2008;101:465. https://doi.org/10.1097/SMJ.0b013e3181684f38
  5. Prasad KC, Prasad SC, Mouli N, Agarwal S. Osteomyelitis in the head and neck. Acta Otolaryngol. 2007;127:194-205. https://doi.org/10.1080/00016480600818054
  6. Van Merkesteyn JP, Groot RH, Van Den Akker HP, Bakker DJ, Borgmeijer-Hoelen AM. Treatment of chronic suppurative osteomyelitis of the mandible. Int J Oral Maxillofac Surg. 1997;26:450-454. https://doi.org/10.1016/S0901-5027(97)80012-4
  7. Singh B, Prasad V, Bhattacharya A, Singh AK, Bhatnagar A, Mittal BR, Gupta KA. Diagnosis of mandibular osteomyelitis in probable coexisting tumor recurrence: Role of Tc-99m ciprofloxacin imaging. Clin Nucl Med. 2008;33:525-527. https://doi.org/10.1097/RLU.0b013e31817e6de9
  8. Koorbusch GF, Fotos P, Goll KT. Retrospective assessment of osteomyelitis: Etiology, demographics, risk factors, and management in 35 cases. Oral Surg Oral Med Oral Pathol. 1992;74:149-154. https://doi.org/10.1016/0030-4220(92)90373-X
  9. Kim S, Jang H. Treatment of chronic osteomyelitis in Korea. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92:394-398. https://doi.org/10.1067/moe.2001.117810
  10. Vezeau PJ, Koorbusch GF, Finkelstein M. Invasive squamous cell carcinoma of the mandible presenting as a chronic osteomyelitis. J Oral Maxillofac Surg. 1990;48:1118-1122. https://doi.org/10.1016/0278-2391(90)90301-H