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Clinical and Radiological Comparison of Femur and Fibular Allografts for the Treatment of Cervical Degenerative Disc Diseases

  • Oh, Hyeong-Seok (Department of Neurosurgery, Busan Wooridul Spine Hospital) ;
  • Shim, Chan Shik (Department of Neurosurgery, Wooridul Spine Centre) ;
  • Kim, Jin-Sung (Department of Neurosurgery, Wooridul Spine Hospital) ;
  • Lee, Sang-Ho (Department of Neurosurgery, Wooridul Spine Hospital)
  • 투고 : 2012.05.18
  • 심사 : 2013.01.15
  • 발행 : 2013.01.28

초록

Objective : This consecutive retrospective study was designed to analyze and to compare the efficacy and outcomes of anterior cervical discectomy and fusion (ACDF) using a fibular and femur allograft with anterior cervical plating. Methods : A total of 88 consecutive patients suffering from cervical degenerative disc disease (DDD) who were treated with ACDF from September 2007 to August 2010 were enrolled in this study. Thirty-seven patients (58 segments) underwent anterior interbody fusion with a femur allograft, and 51 patients (64 segments) were treated with a fibular allograft. The mean follow-up period was 16.0 (range, 12-25) months in the femur group and 19.5 (range, 14-39) months in the fibular group. Cage fracture and breakage, subsidence rate, fusion rate, segmental angle and height and disc height were assessed by using radiography. Clinical outcomes were assessed using a visual analog scale and neck disability index. Results : At 12 months postoperatively, cage fracture and breakage had occurred in 3.4% (2/58) and 7.4% (4/58) of the patients in the femur group, respectively, and 21.9% (14/64) and 31.3% (20/64) of the patients in the fibular group, respectively (p<0.05). Subsidence was noted in 43.1% (25/58) of the femur group and in 50.5% (32/64) of the fibular group. No difference in improvements in the clinical outcome between the two groups was observed. Conclusion : The femur allograft showed good results in subsidence and radiologic parameters, and sustained the original cage shape more effectively than the fibular allograft. The present study suggests that the femur allograft may be a good choice as a fusion substitute for the treatment of cervical DDD.

키워드

참고문헌

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피인용 문헌

  1. Radiologic Changes of Anterior Cervical Discectomy and Fusion Using Allograft and Plate Augmentation: Comparison of Using Fixed and Variable Type Screw vol.10, pp.3, 2013, https://doi.org/10.14245/kjs.2013.10.3.160
  2. Surgical Outcome of a Zero-profile Device Comparing with Stand-alone Cage and Anterior Cervical Plate with Iliac Bone Graft in the Anterior Cervical Discectomy and Fusion vol.11, pp.3, 2014, https://doi.org/10.14245/kjs.2014.11.3.169
  3. Vascularized Fibular Strut Autografts in Spinal Reconstruction after Resection of Vertebral Chordoma or Chondrosarcoma: A Retrospective Series vol.81, pp.1, 2013, https://doi.org/10.1093/neuros/nyw057
  4. Evaluation of bony fusion after anterior cervical discectomy: a systematic literature review vol.28, pp.2, 2013, https://doi.org/10.1007/s00586-018-5820-9
  5. Comparison of the effectiveness and safety of bioactive glass ceramic to allograft bone for anterior cervical discectomy and fusion with anterior plate fixation vol.43, pp.5, 2013, https://doi.org/10.1007/s10143-019-01225-x