Two Cases of Cancer-induced Lymphedema Patients Treated with Oryeongsan

종양으로 인한 이차성 림프부종에 대한 오령산 치험 2례

  • Lee, Ji-Young (Dept. of Internal medicine, Kyung-Hee University Hospital at Gang-dong) ;
  • Chae, Jean (Dept. of Internal medicine, Kyung-Hee University Hospital at Gang-dong) ;
  • Jung, Yee-Hong (Dept. of Sa-sang constitutional medicine, Kyung-Hee University Hospital at Gang-dong) ;
  • Lee, Soo-Kyung (Dept. of Sa-sang constitutional medicine, Kyung-Hee University Hospital at Gang-dong) ;
  • Jung, Hyun-Sik (Graduate school, Dan-Kook University)
  • 이지영 (강동경희대병원 한방내과) ;
  • 채진 (강동경희대병원 한방내과) ;
  • 정의홍 (강동경희대병원 사상체질과) ;
  • 이수경 (강동경희대병원 사상체질과) ;
  • 정현식 (단국대학교 대학원)
  • Published : 2013.09.30

Abstract

Objectives : The purpose of this study was to report two cases which suggest Oryeongsan as a pharmacological treatement option for cancer-induced secondary lymphedema. Methods : The cases were two female patients with peripheral edema. The first was diagnosed with cervical cancer with paraaortic lymph node metastasis and suffered from bilateral edema of the lower extremities. The second was a breast cancer patient with right arm lymphedema, which was aggravated after a weekly regimen of chemotherapy. Oryeongsan was orally administered for 3-4 days to both patients. Results : The symptoms in lower extremities and body weight of the cervical cancer patient decreased. The breast cancer patient did not lose body weight, but pain in upper extremities was reduced. Conclusions : Oryeongsan may potentially be an option for secondary lymphedemas, including cancer-induced lymphedema.

Keywords

References

  1. Sullivan DH, Roberson PK, Bopp MM. Hypoalbuminemia 3 months after hospital discharge: significance for long-term survival. J Am Geriatr Soc 2005;53(7):1222-6. https://doi.org/10.1111/j.1532-5415.2005.53369.x
  2. 강승훈, 황기훈, 심영주, 정호중, 이태화, 김성한. 부인암 관련 하지 림프부종의 유병률 및 위험인자. 대한산부인과학회 2009;52(8):815-20.
  3. Tiwari P, Coriddi M, Salani R, Povoski S. Breast and gynecologic cancer-related extremity lymphedema: a review of diagnostic modalities and management options World J Surg Oncol 2013;11(1):237. https://doi.org/10.1186/1477-7819-11-237
  4. 김정훈, 신현규. 오령산 효능에 관한 기초 실험 연구 문헌 분석. 대한한방내과학회지 2012;33(1) :69-82.
  5. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, National Institutes of Health. National Cancer Institute. Common Terminology Criteria for Adverse Events (CTCAE) version 4.02, 2009 [internet]. [2013.09.28.검색]. Available at: http://evs.nci.nih.gov/ ftp1/CTCAE/Archive/CTCAE_4.02_2009-09- 15_QuickReference_5x7_Locked.pdf.
  6. 오달석, 정소영, 김애란, 강위창, 박지은, 구창모, 외. Loperamide로 억제된 위장관 운동에 대한사관혈의 자침효과: 무작위배정, 단일눈가림, 교차설계, 대조 임상시험. 대한한의학회지 2008; 29(1):1-6.
  7. Casley-Smith JR, Casley-Smith JR. Lymphedema therapy in Australia, complex physical therapy and Benzo-Pyrones over 600 limbs Lymphology 1994;27:622-6.
  8. 보건복지부, 중앙암등록본부. 국가암등록사업 연례 보고서(2010년 암등록통계), 2012 [internet]. [2013.09.28.검색]. Available at: http://ncc.re.kr/ manage/manage03_033_list.jsp
  9. Ridner SH. Pathophysiology of Lymphedema. Semin Oncol Nurs 2013;29(1):4-11. https://doi.org/10.1016/j.soncn.2012.11.002
  10. 정향미, 조명옥. 림프부종 환자의 정서상태와 관련요인, 대한간호학회지 2006;36(5):845-52.
  11. Tunkel RS, Lachmann E. Lymphedema of the limb, An overview of treatment options Postgrad med J 1998;104(4):131-4.
  12. 오수연, 김현아, 정광조, 김정선, 조종관, 유화승. 유방암 여성환자의 림프부종에 대한 림프 배액맛사지의 효과. 대한암한의학회지 2007;12(1) :15-24.
  13. Beng TS, Chin LE. Multiple subcutaneous puncture and stoma bag drainage for gross lower limb edema: A case report J palliat med 2010;13(8):1037-8. https://doi.org/10.1089/jpm.2009.0314
  14. Chen DA. Treating 27 cases of edema in the lower limbs with Wu Ling San Xinjiang Journal of Traditional Chinese Medicine 1998;16(1): 19-20.
  15. Ahn YM, Kho JH, Lee JY, Kang DG, Oryeong-san has different effects on water and electrolyte balance by routes of administration Kor J Ori Med Physiol Pathol 2012;26(3):338-43.
  16. Stason WB, Cannon PJ, Heinemann HO, Laragh JH, Furosemide: A clinical evaluation of its diuretic action Circulation 1966;34:910-20. https://doi.org/10.1161/01.CIR.34.5.910