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Importance of immediate surgical intervention and antifungal treatment for rhinocerebral mucormycosis: a case report

  • Kim, Jin-Geun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Park, Hye Jeong (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Park, Jung Hyun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Baek, Jiwoong (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Hyung Jun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Cha, In-Ho (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Nam, Woong (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University)
  • 투고 : 2013.06.19
  • 심사 : 2013.08.05
  • 발행 : 2013.10.31

초록

Rhinocerebral mucormycosis (RCM) is an opportunistic, potentially life-threatening fungal disease. This infective disease invades not only the facial sinuses, but also the maxilla, zygoma, and rhino-cerebral structures with a massive destruction of the facial skeletons and soft tissue. This disease progresses within various underlying diseases, such as diabetes mellitus, hematologic malignancy, renal failure, and systemic immunodepression. The relationship between mucormycosis and these underlying conditions have been discussed extensively in the literature. The authors studied 6 cases of RCM diagnosed by a tissue biopsy and treated at the department of oral and maxillofacial surgery, from 1997 to 2012. Patients were treated with several kinds of surgical interventions and antifungal agents, and their clinical & radiological signs, underlying conditions, surgical methods, and outcomes were analyzed.

키워드

참고문헌

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피인용 문헌

  1. Combined Orofacial Aspergillosis and Mucormycosis: Fatal Complication of a Recurrent Paediatric Glioma-Case Report and Review of Literature vol.181, pp.9, 2013, https://doi.org/10.1007/s11046-016-0021-8
  2. La mucormycose en ORL. À propos de 4 observations vol.133, pp.2, 2013, https://doi.org/10.1016/j.aforl.2015.01.007
  3. Epidemiology, clinical features, diagnosis and treatment of cerebral mucormycosis in diabetic patients: A systematic review of case reports and case series vol.63, pp.12, 2020, https://doi.org/10.1111/myc.13187