한국의학물리학회지:의학물리 (Progress in Medical Physics)

  • 제24권3호
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  • Pages.176-182
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  • 2013
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  • 2508-4445(pISSN)
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  • 2508-4453(eISSN)
한국의학물리학회 (Korean Society of Medical Physics)
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F-18 FDG PET/CT 전신 영상에서 SUVs 측정에 기반한 조기/정밀 진단 연구

Enhancement of the Early/Precise Diagnosis Based on the Measurement of SUVs in F-18 FDG PET/CT Whole-body Image

  • 박정규 (대구보건대학교 방사선과) ;
  • 김성규 (영남대학교 의과대학 방사선종양학교실) ;
  • 조인호 (영남대학교 의과대학 핵의학교실) ;
  • 공은정 (영남대학교 의과대학 핵의학교실) ;
  • 박명환 (대구보건대학교 방사선과) ;
  • 조복연 (순천향대학교 구미병원 영상의학과)
  • Park, Jeong-Kyu (Department of Radiologic Technology, Daegu Health College) ;
  • Kim, Sung Kyu (Department of Radiation Oncology, Yeungnam University College of Medicine) ;
  • Cho, Ihn-Ho (Department of Nuclear Medicine, Yeungnam University College of Medicine) ;
  • Kong, Eun-Jung (Department of Nuclear Medicine, Yeungnam University College of Medicine) ;
  • Park, Myeong-Hwan (Department of Radiologic Technology, Daegu Health College) ;
  • Cho, Bok-Yeon (Department of Radiology, Soonchunhyang University of Hospital Gumi)
  • 투고 : 2013.08.12
  • 심사 : 2013.09.04
  • 발행 : 2013.09.30
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초록

본 연구의 목적은 건강한 검진자들을 대상으로 F-18 FDG PET/CT 전신 영상에서 진단 수준을 향상하고자 관심부피를 이용하여 정상부위의 SUVs, 즉 SUVLBM, SUVBW, SUVBSA의 데이터를 마련하였다. 각각의 최대치(maximum), 평균치(mean), 표준편차(standard deviation), 역치(threshold)를 제시 하고자 한다. 2012년 7월부터 8월까지 전신 F-18 FDG PET/CT 검사를 시행한 총 31명을 대상으로 SUVs를 측정 하였다. 측정의 정확도를 높이고자 핵의학 전문의의 소견으로 이중에서 26명의 건강한 수검자를 대상으로 하였다. 조영제 사용유무와 관계없이 PET/CT의 SUVs 측정에서 SUVBW의 측정치가 가장 높았으며, SUVLBM, SUVBSA 순으로 나타났다. SUVLBM-최대치를 이용하여 조영제를 사용하지 않은 군과 사용한 군을 비교했을 경우, 조영제를 사용했을 경우 측정치가 증가하는 경향을 보였으며, 8부위 중 간, 대동맥, 요추-5, 소뇌는 매우 유의하게 차이가 있는 것으로 나타났다(p<0.05). PET/CT의 모든 영상의 판독에서 본 SUVs 데이터가 조기정밀/진단 수준을 향상 하는데 기초 자료가 될 것이라고 판단되며, VOI를 이용한 연구가 활발히 이루어지길 기대한다.

Through this research, we measure the data for several SUVs such as SUVLBM, SUVBW, and SUVBSA using volume of interest in order to enhance the diagnostic level in whole-body image for healthy examinees via F-18 FDG PET/CT. Maximum value, mean value, standard deviation, and threshold value for each SUVs are shown. The measurement of SUVs are carried out with 31 examinees who have taken whole-body examination with F-18 FDG PET/CT from July, 2012 to August, 2012. To secure the preciseness of measurement, we selected 26 healthy examinees as a subject of measurement according to diagnostic view of a nuclear-medical doctor. We see from the measurement of SUVs of PET/CT that the value of SUVBW is hightest and followed by SUVLBM and SUVBSA in turn regardless of the use of contrast media. By comparing the SUVLBM-maximum data for the group used contrast media with those for the group used no contrast media, there found a trend that the measured values increase when the contrast media are used. Among them, liver, aorta, lumbar-5, and Cerebellum exhibit significant difference (p<0.05). We conclude that our data for SUVs would be basic references in overall image interpretation, and hope that the research using VOI would be active.

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