Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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Histomorphometric Analysis on Bone Formation Effect of Beta-tricalciumphosphate around Dental Implants in Rabbit Mandibular Body: Pilot Study

토끼의 하악골체부에 식립된 임플란트 주위에서 Beta-tricalciumphosphate 골이식재의 골형성효과에 대한 조직계측학적 연구

  • Pyun, Young-Hoon (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine) ;
  • Kim, Il-Kyu (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine) ;
  • Cho, Hyun-Young (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine) ;
  • Ju, Sang-Hyun (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine) ;
  • Jung, Bum-Sang (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine) ;
  • Pae, Sang-Pill (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine) ;
  • Cho, Hyun-Woo (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Inha University School of Medicine)
  • 편영훈 (인하대학교 의과대학 치과학교실 구강악안면외과) ;
  • 김일규 (인하대학교 의과대학 치과학교실 구강악안면외과) ;
  • 조현영 (인하대학교 의과대학 치과학교실 구강악안면외과) ;
  • 주상현 (인하대학교 의과대학 치과학교실 구강악안면외과) ;
  • 정범상 (인하대학교 의과대학 치과학교실 구강악안면외과) ;
  • 배상필 (인하대학교 의과대학 치과학교실 구강악안면외과) ;
  • 조현우 (인하대학교 의과대학 치과학교실 구강악안면외과)
  • Received : 2013.01.10
  • Accepted : 2013.09.26
  • Published : 2013.09.30
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Abstract

Purpose: The purpose of this study is to assess the effectiveness of beta-tricalciumphosphate (${\beta}$-TCP) as a bone graft material on new bone formation and regeneration of mandible bone defect around dental implants. Methods: Both mandibular sites of ten rabbits were exposed. The experimental subjects were divided into two groups. Rabbits in the control group (right site of the mandible) had dental implants around cortical bone defects, without treatment, while, in the experimental group (left site of the mandible), ${\beta}$-TCP was grafted into the bone defect around the implant. Rabbits were sacrificed after one, two, three, four, and eight weeks, and histomorphometric evaluation and analysis of the bone implant contact rate were performed using an optical microscope. Results: Bone formation rates in the experimental group were greater than those in the control group from one to eight weeks, and percentages of implant surface contacted to bone were greater in the experimental group than in the control group from three weeks after implantation. Conclusion: These results suggest that the bone formation activity around dental implants was increased by osteoconduction activity of ${\beta}$-TCP.

Keywords

References

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