Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지
DOI QR코드

DOI QR Code

Clinical Study on the Efficacy of the Autogenous Tooth Bone Graft Material (AutoBT)

자가치아 뼈 이식재의 유용성에 관한 임상적 연구

  • Han, Min Woo (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Ajou University School of Medicine) ;
  • Lee, Jeong Keun (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Ajou University School of Medicine)
  • 한민우 (아주대학교 의과대학 치과학교실 구강악안면외과) ;
  • 이정근 (아주대학교 의과대학 치과학교실 구강악안면외과)
  • Received : 2013.02.27
  • Accepted : 2013.07.25
  • Published : 2013.07.31
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: This study is to evaluate the efficacy of the autogenous tooth bone graft material, clinically and radiologically, as related to implant installation. Methods: In oral and maxillofacial surgery department of Ajou University Hospital, guided bone regeneration (GBR), implant placement combined with GBR, sinus graft, implant placement combined with sinus graft, and defect filling were performed in 46 patients, using autogenous tooth bone. Among these, 66 implants were inserted with autogenous tooth bone. Implant stability quotient (ISQ) was measured by Osstell Mentor (Integration Diagnostics, Goteborg, Sweden) on 39 implants on the operation date and 4 months later, and on 21 implants 9months on the average at the final setting of restoration. Twenty-eight implants with GBR and sinus graft (GBR group: n=14, sinus graft group: n=14) were evaluated radiologically to measure the resorption of grafted autogenous tooth bone after loading. Results: The average initial stabilization of the installed implants was 67 ISQ, and the average secondary stabilization at 4 months later was 76. The average bone loss of GBR group as measured 8.0 months after application of prosthesis loading was 0.29 mm and the average bone loss of the sinus graft group as measured 7.6 months after application of prosthesis loading was 0.66 mm, respectively. In the histological assessment, formation of the new bone and continuous trabecular bone pattern was identified around autogenous tooth bone. Conclusion: Based on these results, we concluded that autogenous tooth bone is an excellent bone graft material that can substitute the autogenous bone.

Keywords

References

  1. Kim YK, Yeo HH, Ryu CH, Lee HB, Byun UR, Cho JO. An experimental study on the tissue reaction of toothash implanted in mandible body of the mature dog. J Korean Assoc Maxillofac Plast Reconstr Surg 1993;15:129-36.
  2. Kim YK, Yeo HH, Yang IS, Seo JH, Cho JO. Implantation of toothash combined with plaster of paris: experimental study. J Korean Assoc Maxillofac Plast Reconstr Surg 1994;16:122-9.
  3. Kim YK. The experimental study of the implantation of toothash and plaster of paris and guided tissue regeneration using lyodura. J Korean Assoc Oral Maxillofac Surg 1996;22:297-306.
  4. Kim YK, Yeo HH. Transmitted electronic microscopic study about the tissue reaction after the implantation of toothash. J Korean Assoc Oral Maxillofac Surg 1997;23:283-9.
  5. Kim SG, Kim YK, Park JS. Scientific evidence for autogenous tooth bone graft material (AutoBT). J Korean Dent Sci 2009;2:42-5.
  6. Kim SG, Yeo HH, Kim YK. Grafting of large defects of the jaws with a particulate dentin-plaster of paris combination. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;88:22-5. https://doi.org/10.1016/S1079-2104(99)70188-5
  7. Ku HR, Jang HS, Kim SG, et al. Guided tissue regeneration of the mixture of human tooth-ash and Plaster of Paris in dogs. Key Eng Mater 2007;330-332:1327-30. https://doi.org/10.4028/www.scientific.net/KEM.330-332.1327
  8. Kim YK, Kim SG, Byeon JH, et al. Development of a novel bone grafting material using autogenous teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109:496-503. https://doi.org/10.1016/j.tripleo.2009.10.017
  9. Kim SG, Kim HK, Lim SC. Combined implantation of particulate dentine, plaster of Paris, and a bone xenograft (Bio-Oss) for bone regeneration in rats. J Craniomaxillofac Surg 2001;29:282-8. https://doi.org/10.1054/jcms.2001.0236
  10. Ike M, Urist MR. Recycled dentin root matrix for a carrier of recombinant human bone morphogenetic protein. J Oral Implantol 1998;24:124-32. https://doi.org/10.1563/1548-1336(1998)024<0124:RDRMFA>2.3.CO;2
  11. Gao J, Symons AL, Bartold PM. Expression of transforming growth factor-beta 1 (TGF-beta1) in the developing periodontium of rats. J Dent Res 1998;77:1708-16. https://doi.org/10.1177/00220345980770090701
  12. Saygin NE, Tokiyasu Y, Giannobile WV, Somerman MJ. Growth factors regulate expression of mineral associated genes in cementoblasts. J Periodontol 2000;71:1591-600. https://doi.org/10.1902/jop.2000.71.10.1591
  13. Emecen P, Akman AC, Hakki SS, et al. ABM/P-15 modulates proliferation and mRNA synthesis of growth factors of periodontal ligament cells. Acta Odontol Scand 2009;67:65-73. https://doi.org/10.1080/00016350802555525
  14. Kim YK, Kim SG, Yun PY, et al. Autogenous teeth used for bone grafting: a comparison with traditional grafting materials. Oral Surg Oral Med Oral Pathol Oral Radiol 2012;pii:S2212- 4403(12)00365-3. [Epub]
  15. Chung JH, Lee JH. Study of bone healing pattern in extraction socket after application of demineralized dentin matrix material. J Korean Assoc Oral Maxillofac Surg 2011;37:365-74. https://doi.org/10.5125/jkaoms.2011.37.5.365
  16. Park SM, Um IW, Kim YK, Kim KW. Clinical application of auto-tooth bone graft material. J Korean Assoc Oral Maxillofac Surg 2012;38:2-8. https://doi.org/10.5125/jkaoms.2012.38.1.2
  17. Jeong HR, Hwang JH, Lee JK. Effectiveness of autogenous tooth bone used as a graft material for regeneration of bone in miniature pig. J Korean Assoc Oral Maxillofac Surg 2011;37:375-9. https://doi.org/10.5125/jkaoms.2011.37.5.375

Cited by

  1. Sinus floor augmentation using a mineralized freeze-dried bone graft combined with recombinant human bone morphogenetic protein-2: clinical and histological results of three cases vol.45, pp.4, 2013, https://doi.org/10.21851/obr.45.04.202112.237