DOI QR코드

DOI QR Code

High-Speed SD-OCT for Ultra Wide-field Human Retinal Three Dimensions Imaging using GPU

병렬처리 그래픽 기술 기반의 Spectral Domain-Optical Coherence Tomography를 이용한 3차원 광 대역 망막 촬영

  • Park, Kibeom (School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Cho, Nam Hyun (School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Wijesinghe, Ruchire Eranga Henry (School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Kim, Jeehyun (School of Electrical Engineering and Computer science, Kyungpook National University)
  • 박기범 (경북대학교 전자전기컴퓨터공학부 대학원) ;
  • 조남현 (경북대학교 전자전기컴퓨터공학부 대학원) ;
  • ;
  • 김지현 (경북대학교 전자전기컴퓨터공학부 대학원)
  • Received : 2013.05.16
  • Accepted : 2013.07.23
  • Published : 2013.09.30

Abstract

We have developed an ultra wide-field of view Optical Coherence Tomography(OCT) which has capability to 2D and 3D views of cross-sectional structure of in vivo human retina. Conventional OCT has a limitation in visualizing the entire retina due to a reduced field of view. We designed an optical setup to significantly improve the lateral scanning range to be more than 20 mm. The entire human retinal structure in 2D and 3D was reported in this paper with the developed OCT system. Also, we empirically searched an optimized image size for real time visualization by analyzing variation of the frame rate with different lateral scan points. The size was concluded to be $1024{\times}2000{\times}300$ pixels which took 9 seconds for visualization.

Keywords

References

  1. D. Huang, E.A. Swanson, C.P. Lin, J.S. Schuman, W.G. Stinson, W. Chang, M. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, "Optical coherence tomography," Science, vol. 254, no. 5035, pp. 1178-1181, 1991. https://doi.org/10.1126/science.1957169
  2. B.E. Bouma and G.J. Tearney, Handbook of Optical Coherence Tomography., New York, Marcel Dekker, Inc, 2002.
  3. A.F. Fercher, W. Drexler, C.K. Hitzenberger, and T. Lasser, "Optical coherence tomography-principles and applications," Rep. Prog. Phys. vol. 66, pp. 239-303, 2003. https://doi.org/10.1088/0034-4885/66/2/204
  4. Y.K. Tao, M. Zhao, and J.A. Izatt, "High-speed complex conjugate resolved retinal spectral domain optical coherence tomography using sinusoidal phase modulation," Opt. Lett, no. 32, pp. 2918-2920, 2007.
  5. K. Zhang, and J.U. Kang, "Real-time 4D signal processing and visualization using graphics processing unit on a regular nonlinear-k Fourier-domain OCT system," Opt. Express, vol. 18, no. 11, pp. 11772-1178, 2010. https://doi.org/10.1364/OE.18.011772
  6. B. Povazay, B. Hermann, B. Hofer, V. Kajic´ , E. Simpson, T. Bridgford, and W. Drexler, "Wide-Field Optical Coherence Tomography of the Choroid In Vivo" IOVS, vol. 50, no. 4, pp. 1856-1863, 2009.
  7. NH Cho, U. Jung, S. Kim, W. Jung, J. Oh, HW Kang, J. Kim, "Speed SD-OCT System Using GPU Accelerated Mode for in vivo Human Eye Imaging" Journal of the Optical Society of Korea, vol. 17, no. 1, pp. 68-72, 2013. https://doi.org/10.3807/JOSK.2013.17.1.068
  8. M. Jeon, U. Jung, J.-W. Song, J. Kim, J. Oh, J. Eom, C.-S. Kim, and Y.-H. Park, "Frequency swept laser at 1300 nm using a wavelength scanning filter based on a rotating slit disk," J. Opt. Soc. Korea, no. 13, pp. 330-334, 2009. https://doi.org/10.3807/JOSK.2009.13.3.330
  9. L. An, P. Li, Go. Lan, D. Malchow, RK. Wang, "High-resolution 1050 nm spectral domain retinal optical coherence tomography at 120 kHz A-scan rate with 6.1 mm imaging depth" B. Opt. Express, vol. 4, no. 2, pp. 245-259, 2013. https://doi.org/10.1364/BOE.4.000245
  10. Spectral Domain Optical Coherence Tomography(SD-OCT) [https://www.heidelbergengineering.com/international/products/spectralis/technology/spectral-domain-oct]
  11. RWS. Chen, JS. Ducker, G. JG, Fujumoto, "Speed and Resolution Improve in Newest OCT", Review of Opthalmology, pp. 84-88, 2007.