References
- The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. 1997. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 20: 1183-1197. https://doi.org/10.2337/diacare.20.7.1183
- DeFronzo RA. 1997. Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 5: 177-269.
- Srinivasan K. 2005. Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts. Int J Food Sci Nutr 56: 399-414. https://doi.org/10.1080/09637480500512872
- Virtanen AL, Matikkala EJ. 1976. The isolation of S-methyl-L-cysteine sulphoxide and S-n-propyl-L-cysteine sulphoxide from onion (Allium cepa) and the antibiotic activity of crushed onion. Acta Chem Scand 13: 1898-1900.
- Block E. 1985. The chemistry of garlic and onions. Sci Am 252: 94-99.
- Patil BS, Pike LM. 1995. Distribution of quercetin contents in different rings various coloured onion (Allium cepa L.) cultivars. J Hortic Sci 70: 643-650. https://doi.org/10.1080/14620316.1995.11515338
- Galeone C, Pelucchi C, Levi F, Negri E, Franceschi S, Talamini R, Giacosa A, La Vecchia C. 2006. Onion and garlic use and human cancer. Am J Clin Nutr 84: 1027-1032. https://doi.org/10.1093/ajcn/84.5.1027
- Belman S. 1983. Onion and garlic oils inhibit tumor promotion. Carcinogenesis 4: 1063-1065. https://doi.org/10.1093/carcin/4.8.1063
- Mennen LI, Sapinho D, de Bree A, Arnault N, Bertrais S, Galan P, Hercberg S. 2004. Consumption of foods rich in flavonoids is related to a decreased cardiovascular risk in apparently healthy French women. J Nutr 134: 923-926. https://doi.org/10.1093/jn/134.4.923
- Sakai Y, Murakami T, Yamamoto Y. 2003. Antihypertensive effects of onion on NO synthase inhibitor-induced hypertensive rats and spontaneously hypertensive rats. Biosci Biotechnol Biochem 67: 1305-1311. https://doi.org/10.1271/bbb.67.1305
- Kumari K, Augusti KT. 2007. Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats. J Ethnopharmacol 109: 367-371. https://doi.org/10.1016/j.jep.2006.07.045
- Babu PS, Srinivasan K. 1997. Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus. Mol Cell Biochem 175: 49-57. https://doi.org/10.1023/A:1006881027166
- Kumari K, Mathew BC, Augusti KT. 1995. Antidiabetic and hypolipidemic effects of S-methyl cysteine sulfoxide isolated from Allium cepa Linn. Indian J Biochem Biophys 32: 49-54.
- Kumari K, Augusti KT. 2002. Antidiabetic and antioxidative effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa Linn) as compared to standard drugs in alloxan diabetic rats. Indian J Exp Biol 40: 1005-1009.
- El-Demerdash FM, Yousef MI, El-Naga NI. 2005. Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food Chem Toxicol 43: 57-63. https://doi.org/10.1016/j.fct.2004.08.012
- Campos KE, Diniz YS, Cataneo AC, Faine LA, Alves MJ, Novelli EL. 2003. Hypoglycemic and antioxidant effects of onion, Allium cepa: dietary onion addition, antioxidant activity and hypoglycemic effects on diabetic rats. Int J Food Sci Nutr 54: 241-246. https://doi.org/10.1080/09637480120092062
- Jelodar GA, Maleki M, Motadayen MH, Sirus S. 2005. Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats. Indian J Med Sci 59: 64-69. https://doi.org/10.4103/0019-5359.13905
- Sheela CG, Kumud K, Augusti KT. 1995. Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats. Planta Med 61: 356-357. https://doi.org/10.1055/s-2006-958099
- Like AA, Rossini AA. 1976. Streptozotocin-induced pancreatic insulities: new model of diabetes mellitus. Science 193: 415-417. https://doi.org/10.1126/science.180605
- Jafari MA, Aslam M, Javad K, Singh S. 2000. Effect of Punica granatum L. (flowers) on blood glucose level in normal and alloxan induced diabetic rats. J Ethnopharmacol 70: 309-314. https://doi.org/10.1016/S0378-8741(99)00170-1
- Gilman AG, Rall TW, Nies AS, Tayer P. 1990. Goodman and Gilman's the pharmacological basis of therapeutics. 8th ed. Pergamon Press, New York, NY, USA. p 1317-1322.
- Bhushan S. 1984. Effect of oral administration of raw onion on glucose tolerance test of diabetics: a comparison with tolbutamide. Curr Med Pract 28: 712-715.
- Eldin IMT, Ahmed EM, Abd Elwahab HM. 2009. Hypoglycemic activity and regeneration of pancreatic beta-cells produced by Allium cepa in alloxan-induced diabetic rats. Omdurman Journal of Pharmaceutical 1: 562-568.
- Taj Eldin IM, Ahmed EM, Elwahab HMA. 2010. Preliminary study of the clinical hypoglycemic effects of Allium cepa (red onion) in type 1 and type 2 diabetic patients. Environ Health Insights 4: 71-77.
- Yeo J, Kang YM, Cho, SI, Jung MH. 2011. Effects of a multi-herbal extract on type 2 diabetes. Chin Med 6: 10. https://doi.org/10.1186/1749-8546-6-10
- Fonseca SG, Burcin M, Gromada J, Urano F. 2009. Endoplasmic reticulum stress in beta-cells and development of diabetes. Curr Opin Pharmacol 9: 763-770. https://doi.org/10.1016/j.coph.2009.07.003
-
Araki E, Oyadomari S, Mori M. 2003. Impact of endoplasmic reticulum stress pathway on pancreatic
$[\beta]$ -cells and diabetes mellitus. Exp Biol Med 228: 1213-1217. https://doi.org/10.1177/153537020322801018 -
Kaufman RJ, Back SH, Song B, Han J, Hassler J. 2010. The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in
$[\beta]$ -cells. Diabetes Obes Metab 1: 99-107. - Ali M, Thomson M, Afzal M. 2000. Garlic and onions: their effect on eicosanoid metabolism and its clinical relevance. Prostaglandins Leukot Essent Fatty Acids 62: 55-73. https://doi.org/10.1054/plef.1999.0124
Cited by
- Antidiabetic Activity ofArtemisia amygdalinaDecne in Streptozotocin Induced Diabetic Rats vol.2014, 2014, https://doi.org/10.1155/2014/185676
- Antidiabetic Effect of Oleuropein from Olea europaea Leaf against Alloxan Induced Type 1 Diabetic in Rats vol.59, pp.0, 2016, https://doi.org/10.1590/1678-4324-2016150116
- Nonthermal pasteurization of onion juice by continuous UV-C reactor pp.01496085, 2018, https://doi.org/10.1111/jfs.12533
- Anti-diabetic effects of water extract from the dietary mushroom Neolentinus lepideus in type 2 diabetic db/db mice vol.15, pp.3, 2013, https://doi.org/10.14480/jm.2017.15.3.99
- Amelioration of hyperglycemia and associated metabolic abnormalities by a combination of fenugreek (Trigonella foenum-graecum) seeds and onion (Allium cepa) in experimental diabetes vol.28, pp.5, 2017, https://doi.org/10.1515/jbcpp-2015-0140
- Amelioration of hyperglycemia and associated metabolic abnormalities by a combination of fenugreek (Trigonella foenum-graecum) seeds and onion (Allium cepa) in experimental diabetes vol.28, pp.5, 2017, https://doi.org/10.1515/jbcpp-2015-0140
- Natural Hydrogen Sulfide Donors from Allium sp. as a Nutraceutical Approach in Type 2 Diabetes Prevention and Therapy vol.11, pp.7, 2013, https://doi.org/10.3390/nu11071581
- Protein Isolate from Parkia biglobosa Seeds Improves Dyslipidaemia and Cardiac Oxidative Stress in Streptozotocin-Induced Diabetic Rats vol.8, pp.10, 2019, https://doi.org/10.3390/antiox8100481
- Protective role of Allium cepa Linn (onion) juice on maternal dexamethasone induced alterations in reproductive functions of female offspring of Wistar rats vol.4, pp.None, 2013, https://doi.org/10.1016/j.crphys.2021.06.001
- Phytochemical constituents of sterol‐rich fraction from Allium cepa L. and its cytotoxic effect on human embryonic kidney (HEK293) cells vol.45, pp.3, 2013, https://doi.org/10.1111/jfbc.13586