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Relationship Among Serum Lipid levels, Obesity and Blood Pressure in Health Examined Adult Women

건강검진 수진 성인 여성의 혈청지질과 비만 및 혈압과의 관련성

  • Park, Sung-Kyeong (Department of Beauty Art & Skin Care, Daejeon Health Science College) ;
  • Cho, Young-Chae (Department of Preventive Medicine and Public Health, Chungnam National University School of Medicine and Research Institute for Medical Sciences)
  • 박승경 (대전보건대학 피부미용과) ;
  • 조영채 (충남대학교 의학전문대학원 예방의학교실 및 의학연구소)
  • Received : 2013.06.05
  • Accepted : 2013.09.06
  • Published : 2013.09.30

Abstract

The present study was intended to reveal the relationships between serum lipid levels and various factors of obesity and blood pressure. The study subjects were 1,838 adult women measured at a mass health screening during the period from January through December, 2011. TC, TG, HDL-C, LDL-C, SBP, DBP, degree of obesity, body fat rate were measured and the relation between these obesity and blood pressure measurements to serum lipid levels were studied. As a results, TC, TG, LDL-C, body fat rate and degree of obesity increased linearly with advancing age. TC, TG and LDL-C increased linearly with increasing blood pressure, and these values were higher in hypertension group than that of normal group. TC, TG and SBP increased linearly with increasing degree of obesity, and these values were higher in obesity group than that of normal group. HDL-C decreased linearly with increasing degree of obesity, and these values were lower in obesity group than that of normal group. TC, TG, HDL-C, degree of obesity, body fat rate was positive correlation with each others, but these values negatively correlated to HDL-C. Principal component analysis, showed that subjects could be divided into the group having the hypertensive group(1st principal component), the obesity group(2nd principal component), the hyperlipidemia group(3rd principal component), and HDL-C(4th principal component). In multiple regression analysis, age, TC, TG and body fat rate were affected to HDL-C. Above results suggest that higher the degree of obesity and blood pressure, the higher the serum lipid levels.

본 연구는 혈청지질과 비만 및 혈압과의 관련성을 검토하기 위하여 2011년 1월부터 12월까지 1년 동안에 대전광역시의 한 대학병원에서 종합건강검진을 받았던 30세에서 69세의 여성 1,381명을 대상으로 TC, TG, HDL-C, LDL-C, SBP, DBP, 비만도, 체지방률을 측정하여 혈청지질과 비만 및 혈압과의 관련성을 분석하였다. 연구결과, TC, TG, LDL-C, 비만도, 체지방률은 30대에서부터 60대에 걸쳐 단계적으로 상승하는 경향을 보였다. TC, TG 및 LDL-C는 혈압이 높아짐에 따라 상승하였으며, 정상혈압군에 비해 고혈압군에서 유의하게 높은 값을 보였다. TC, TG, SBP 는 비만도가 높아짐에 따라 단계적으로 상승하였고, 정상군에 비해 비만군에서 유의하게 높았으며, HDL-C는 비만도가 높아짐에 따라 감소하는 경향을 보였고, 정상군에 비해 비만군에서 유의하게 낮았다. TC, TG, LDL-C, 체지방률 및 비만도는 상호간에 유의한 정상관을 보인 반면, HDL-C와는 음의 상관을 보였다. 주성분분석 결과 제1주성분은 고혈압 인자, 제2주성분은 비만관련 인자, 제3주성분은 연령과 고지혈증 인자, 제4주성분은 고단백지콜레스테롤 인자가 선정되었다. HDL-C와 관련된 요인을 다중회귀분석을 사용하여 검토한 결과 HDL-C에 영향을 미치는 변수로는 연령, TC, TG 및 체지방률이 선정되었다. 위와 같은 결과는 비만도가 높고 혈압이 높은 군일수록 혈청지질치가 높아짐을 시사하고 있다.

Keywords

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