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Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran

  • Rassouli, Maryam (Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Razmi, Golam Reza (Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Movassaghi, Ahmad Reza (Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Bassami, Mohammad Reza (Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Sami, Mehrdad (Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad)
  • 투고 : 2012.06.23
  • 심사 : 2012.11.14
  • 발행 : 2013.03.31

초록

The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (${\kappa}=0.73$, 0.8) and with no significant difference among different fetal age groups (p > 0.05).

키워드

참고문헌

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피인용 문헌

  1. Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods vol.40, pp.1, 2016, https://doi.org/10.1007/s12639-014-0467-x
  2. Molecular Diagnosis and Pathological Study of Toxoplasma gondii in Aborted Caprine and Ovine Fetuses in Borderline of Iran-Iraq vol.65, pp.1, 2020, https://doi.org/10.2478/s11686-019-00147-4