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8례의 메켈세포암종의 후향적 연구

A Retrospective Analysis of Eight Cases of Merkel Cell Carcinoma

  • 오승일 (서울대학교 의과대학 성형외과학교실) ;
  • 진웅식 (서울대학교 의과대학 성형외과학교실) ;
  • 장학 (서울대학교 의과대학 성형외과학교실) ;
  • 권성택 (서울대학교 의과대학 성형외과학교실) ;
  • 민경원 (서울대학교 의과대학 성형외과학교실)
  • Oh, Seung Il (Department of Plastic and Reconstructive Surgery, Seoul National University School of Medicine) ;
  • Jin, Ung Sik (Department of Plastic and Reconstructive Surgery, Seoul National University School of Medicine) ;
  • Chang, Hak (Department of Plastic and Reconstructive Surgery, Seoul National University School of Medicine) ;
  • Kwon, Sung Tack (Department of Plastic and Reconstructive Surgery, Seoul National University School of Medicine) ;
  • Minn, Kyung Won (Department of Plastic and Reconstructive Surgery, Seoul National University School of Medicine)
  • 투고 : 2013.02.01
  • 심사 : 2013.03.15
  • 발행 : 2013.04.09

초록

Background: Merkel cell carcinoma (MCC) is a rare locally aggressive cutaneous neuroendocrine carcinoma with a high incidence of local recurrence, regional lymph node metastasis, followed by distant metastasis. Because of shortage of the retrospective study, standard treatment has not been established. The purpose of this study was to present the surgical treatment and outcome of 8 patients with MCC. Methods: We report our experiences with 8 patients who underwent treatment for MCC at our institution from 2000 through 2012. Two men and 6 women received treatment for MCC. The mean age was 76.4 years (range, 53 to 93 years). Results: The follow-up period ranged from 7 to 26 months (mean, 22.9). During the follow-up period, three of 8 patients had a relapse (mean time before recurrence, 10 months; 1 month, 7 months, and 22 months). After primary surgery, 3 patients underwent radiotherapy, and 1 patient received chemotherapy. Conclusion: MCC is an aggressive skin cancer with a high rate of local recurrence. Complete surgical excision is the mainstay of local treatment, but adjuvant radiotherapy should be considered for better local control.

키워드

피인용 문헌

  1. A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature vol.31, pp.3, 2013, https://doi.org/10.5021/ad.2019.31.3.272