Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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Voice Analysis before and after Radioactive Iodine Ablation in Patients with Total Thyroidectomy

적갑상선 전절제술 환자의 방사성 동위원소치료 전.후 음성의 변화에 대한 연구

  • Hong, Ki Hwan (Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital) ;
  • Seo, Eun Ji (Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital) ;
  • Lee, Hyun Doo (Otolaryngology-HNS, Chonbuk National University Medical School) ;
  • Yoon, Yun Sub (Otolaryngology-HNS, Chonbuk National University Medical School) ;
  • Lim, Seok Tae (Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital)
  • 홍기환 (전북대학교 임상의학연구소-전북대학교병원 의생명연구원) ;
  • 서은지 (전북대학교 임상의학연구소-전북대학교병원 의생명연구원) ;
  • 이현두 (전북대학교 이비인후과학교실) ;
  • 윤연섭 (전북대학교 이비인후과학교실) ;
  • 임석태 (전북대학교 임상의학연구소-전북대학교병원 의생명연구원)
  • Received : 2013.04.30
  • Accepted : 2013.05.21
  • Published : 2013.06.30
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Abstract

Background and Objectives:This study is to objectively compare and analyze the acoustic changes in the patients with total thyroidectomy before and after RI therapy. Subjects and Methods:For this study, a total of 50 patients with total thyroidectomy were participated as subjects. Voice samples were obtained at the time of post-operation (Post-OP), before high-dose radioactive iodine therapy (Pre-RIT), and after high-dose radioactive iodine therapy (Post-RIT). Acoustic analysis, the maximum phonation time and K-VHI (Korea-Voice handicap index) were used for subjective evaluation. Results:According to the comparison analysis of the three periods, mFo (Hz) was significantly reduced in all of the vowels /a/ and /i/ as the hormone was discontinued. This can be related to the reduction in vocal range. As thyroid hormone was discontinued, Shim (%) and APQ (%) values, which are the parameters related to the degree of aggressiveness, showed a significant increase in the middle vowel /a/. As thyroid hormone was discontinued, emotional index was significantly decreased in VHI (voice handicap index). Conclusion:These results can be assumed that thyroid hormone suspension is related to the increased changes in the vocal intensity, the increase in noise and the reduction in vocal range. Emotionally, these data can be assumed that the responsive factors of one's own voice disorders were significantly decreased in the patients with vocal handicap.

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