DOI QR코드

DOI QR Code

The follow up study after massive outbreak of Akabane and bovine ephemeral fever viruses in Korea

  • Yang, Dong-Kun (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA) ;
  • Kim, Sun-Young (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA) ;
  • Kim, Ha-Hyun (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA) ;
  • Kang, Mi-Sun (Namwon-Branch, Institute of Live Stock and Veterinary Reasearch) ;
  • Nah, Jin-Ju (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA) ;
  • Choi, Sung-Suk (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA) ;
  • Seok, Kum-Ok (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA) ;
  • Cho, Jong-Suk (Institute of Biotechnology in MEDEXX) ;
  • Song, Jae-Young (Viral Disease Division, Animal and Plant Quarantine Agency, MAFRA)
  • Received : 2013.05.22
  • Accepted : 2013.06.29
  • Published : 2013.09.30

Abstract

Since a large number of Akabane and bovine ephemeral fever (BEF) infection occurred in the southern part of Korea in 2010, recent information about seroprevalence of Akabane virus (AKAV) and bovine ephemeral fever virus (BEFV) has been required for preventing both diseases. In this study, serological assay against AKAV and BEFV using virus neutralization assay was conducted using 1,743 bovine sera collected from Namwon, Miryang, Yeongju and Uljin which located in Southern part of Korea from March to May in 2012. The overall seropositive rates for AKAV and BEFV were found to be 49.8% and 1.2%, respectively. The regional distribution of seroprevalence for AKAV ranged from 18.1% to 63.7%. Seroprevalences of AKAV were 63.7% in Miryang, 62.3% in Uljin, 50.7% in Namwon, and 18.1% in Yeongju. The seropositive rates for AKAV in southern part of Korea were higher than the annual average at the national level. On the other hand, seropositive rates of BEFV in four regions were from 0.3 to 3.1%. In detail, regional seroprevalences were 3.1% in Miryang, 2.0% in Uljin, and 1.7% in Yeongju, and 0.3% in Namwon. Even only one year after massive outbreaks, overall seropositive rates were very low, similar to the annual average at the nation level. This result indicates that many number of cattle infected with BEFV may be replaced by new born calf or cattle in farm may not be immunized with vaccines. To prevent another epidemic, a national wide warning should be issued and more aggressive control measure must be implied. Recent global warming phenomenon could lead to more vigorous activity of haematophagous vectors and it is possible that arboviral diseases such as AKAV and BEFV are increased. Therefore, continuous sero-monitoring and extensive vaccination combined with control of haematophagous vectors are important to effectively prevent and control diseases caused by AKAV and BEFV.

Keywords

References

  1. Akashi H, Kaku Y, Kong XG, Pang H. 1997. Sequence determination and phylogenetic analysis of the Akabane bunyavirus S RNA genome segment. J Gen Virol 78: 2847-2851. https://doi.org/10.1099/0022-1317-78-11-2847
  2. Bak UB, Lim CH, Cheong CK, Hwang WS, Cho MR. 1980. Outbreaks of Akabane disease of cattle in Korea. Korean J Vet Res 20: 65-78.
  3. Dhillon J, Cowley JA, Wang Y, Walker PJ. 2000. RNA polymerase (L) gene and genome terminal sequences of ephemeroviruses bovine ephemeral fever virus and Adelaide River virus indicate a close relationship to vesiculoviruses. Virus Res 70: 87-95. https://doi.org/10.1016/S0168-1702(00)00215-X
  4. Elliott RM.1990. Molecular biology of the Bunyaviridae. J Gen Virol 71: 501-522. https://doi.org/10.1099/0022-1317-71-3-501
  5. Farag MA, al-Sukayran A, Mazloum KS, al-Bukomy AM. 1998. Epizootics of bovine ephemeral fever on dairy farms in Saudi Arabia. Rev Sci Tech 17: 713-722. https://doi.org/10.20506/rst.17.3.1127
  6. Hsieh YC, Chen SH, Chou CC, Ting LJ, Itakura C, Wang FI. 2005. Bovine ephemeral fever in Taiwan (2001-2002) J Vet Med Sci 67: 411-416. https://doi.org/10.1292/jvms.67.411
  7. Jun Q, Qingling M, Zaichao Z, Kuojun C, Jingsheng Z, Minxing M, Chuangfu C. 2012. A serological survey of Akabane virus infection in cattle and sheep in northwest China. Trop Anim Health Prod 44: 1817-1820. https://doi.org/10.1007/s11250-012-0168-3
  8. Kang WC, Kim EJ, Hyun KJ, Cheon CI, Kim HS, Lee DS. 2000. Isolation, identification and epidemiological study of Akabane virus on Jeju-do. Korean J Vet Serv 23: 93-102.
  9. Kim YH, Kweon CH, Tark DS, Lim SI, Yang DK, Hyun BH, Song JY, Hur W, Park SC. 2011. Development of inactivated trivalent vaccine for the teratogenic Aino, Akabane and Chuzan viruses. Biologicals 39: 152-157. https://doi.org/10.1016/j.biologicals.2011.02.004
  10. Kono R, Ohtsuki H, Okanobu H, Kinugasa K. 2005. Displacement of rectus muscle pulleys by torsional muscle surgery for treatment of full macular translocationinduced incyclotropia. Am J Ophthalmol 140: 144-146. https://doi.org/10.1016/j.ajo.2004.12.034
  11. Kurogi H, Akiba K, Inaba Y, Matumoto M. 1987. Isolation of Akabane virus from the biting midge Culicoides oxystoma in Japan. Vet Microbiol 15: 243-248. https://doi.org/10.1016/0378-1135(87)90078-2
  12. Lee JK, Park JS, Choi JH, Park BK, Lee BC, Hwang WS, Kim JH, Jean YH, Haritani M, Yoo HS, Kim DY. 2002. Encephalomyelitis associated with Akabane virus infection in adult cows. Vet Pathol 39: 269-273. https://doi.org/10.1354/vp.39-2-269
  13. Liao YK, Lu YS, Goto Y, Inaba Y. 1996. The isolation of Akabane virus (Iriki strain) from calves in Taiwan. J Basic Microbiol 36: 33-39. https://doi.org/10.1002/jobm.3620360108
  14. Lim SI, Kweon CH, Tark DS, Kim SH, Yang DK. 2007. Sero-survey on Aino, Akabane, Chuzan, bovine ephemeral fever and Japanese encephalitis virus of cattle and swine in Korea. J Vet Sci 8: 45-49. https://doi.org/10.4142/jvs.2007.8.1.45
  15. Mohamed ME, Mellor PS, Taylor WP. 1996. Akabane virus: serological survey of antibodies in livestock in the Sudan. Rev Elev Med Vet Pays Trop 49: 285-288.
  16. Nakajima Y, Takahashi E, Konno S. 1980. Encephalitogenic effect of Akabane virus on mice, hamsters and guinea pigs. Natl Inst Anim Health Q (Tokyo) 20: 81-82.
  17. Park BK, Chang CH, 1992. Studies on an attenuated live attenuated Akabane virus vaccine against Akabane disease. Res Rept RDA(V) 34: 20-26.
  18. Shin YK, Oem JK, Yoon S, Hyun BH, Cho IS, Yoon SS, Song JY. 2009. Monitoring of Five Bovine Arboviral Diseases Transmitted by Arthropod Vectors in Korea. J Bacteriol Virol 39: 353-362. https://doi.org/10.4167/jbv.2009.39.4.353
  19. Tsutsui T, Yamamoto T, Hayama Y, Akiba Y, Nishiguchi A, Kobayashi S, Yamakawa M. 2009. Duration of maternally derived antibodies against Akabane virus in calves: survival analysis. J Vet Med Sci 71: 913-918. https://doi.org/10.1292/jvms.71.913
  20. Walker PJ, Byme KA, Riding GA, Cowley JA, Wang Y, McWilliam SM. 1992. The genome of bovine ephemeral fever rhabdovirus contains two related glycoprotein genes. Virology 191: 49-61. https://doi.org/10.1016/0042-6822(92)90165-L
  21. Walker PJ, Keren AB, Daisy HC, Denise LD, Doolan, YongHong W. 1991. Proteins of bovine ephemeral fever virus. J Gen Virol 72: 67-74. https://doi.org/10.1099/0022-1317-72-1-67
  22. Walker PJ, Wang Y, Cowley JA, McWilliam SM, Prehaud CJ. 1994. Structural and antigenic analysis of the nucleoptotein of bovine ephemeral fever rhabdovirus. J Gen Virol 75: 1889-1899. https://doi.org/10.1099/0022-1317-75-8-1889
  23. Wunner WH, Larson JK, Dietzschold B, Smith CL.1988. The molecular biology of rabies viruses. Rev Infect Dis 4: 771-784.
  24. Yang DK, Kim YH, Kim BH, Kweon CH, Yoon SS, Song JY, Lee SH. 2008. Characterization of Akabane virus (KV0505) from cattle in Korea. Korean J Vet Res 48: 61-66.
  25. Zheng FY, Lin GZ, Qiu CQ, Zhou JZ, Cao XA, Gong XW. 2010. Serological detection of bovine ephemeral fever virus using an indirect ELISA based on antigenic site G1 expressed in Pichia pastoris. Vet J 185: 211-215. https://doi.org/10.1016/j.tvjl.2009.06.002

Cited by

  1. 최근 10년간 국내 소 질병 원인체에 관한 문헌적 고찰 vol.43, pp.3, 2020, https://doi.org/10.7853/kjvs.2020.43.3.113