Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
권호 표지
DOI QR코드

DOI QR Code

Manganese(II) and Dioxomolybdenum(VI) Complexes with Monobasic Bidentate Schiff Bases : Synthesis, Characterization and Biological Investigation

  • Garg, Rekha (Department of Chemistry, University of Rajasthan) ;
  • Kumari, Anita (Department of Chemistry, University of Rajasthan) ;
  • Joshi, S.C. (Department of Zoology, University of Rajasthan) ;
  • Fahmi, Nighat (Department of Chemistry, University of Rajasthan)
  • Received : 2013.03.08
  • Accepted : 2013.05.16
  • Published : 2013.08.20
Download PDF
⟨ Previous Next ⟩

Abstract

A new series of Mn(II) and Mo(VI) complexes containing the Schiff bases hydrazinecarbothioamide and hydrazinecarboxamide of 5,6-dimethyl-1H-indol-2,3-dione have been synthesized. The nature of bonding and the stereochemistry of the complexes have been deduced from elemental analyses, molecular weight determinations and spectral studies viz. electronic IR, ESR, $^1H$ NMR and $^{13}C$ NMR and X-ray diffraction spectral studies. The magnetic moment values of the manganese(II) complexes are in the range of 5.80-6.15 B.M. suggesting a high spin state of manganese in these complexes. The spectral data are consistent with a tetrahedral geometry around Mn(II) and an octahedral geometry for Mo(VI), in which the ligands act as bidentate chelating agents, coordinated through the nitrogen and sulfur/oxygen atoms. The ligands and their metal complexes have been tested against a number of pathogenic fungi and bacteria at different concentrations and were found to possess sufficient fungicidal and bactericidal properties. Further, the complexes were also tested for their antifertility activity in male albino rats and the results were indeed positive.

Keywords

References

  1. Kulkarni, A. K.; Avaji, P. G.; Bagihalli, G. B.; Badami, P. S.; Patil, S. A. J. Coord. Chem. 2009, 62, 481. https://doi.org/10.1080/00958970802226387
  2. Nejo, A. A.; Kolawole, G. A.; Nejo, A. O. J. of Coord. Chem. 2010, 63, 4398. https://doi.org/10.1080/00958972.2010.532871
  3. Mohamed, G. G.; Omar, M. M.; Hindy, A. M. Turk. J. Chem. 2006, 30, 361.
  4. Biyala, M. K.; Singh, R. V..; Phosphorus, Sulfur Silicon Relat. Elements 2006, 181, 1477. https://doi.org/10.1080/10426500500330869
  5. Chandra, S.; Tyagi, M. J. Serb. Chem. Soc. 2008, 73, 727. https://doi.org/10.2298/JSC0807727C
  6. Abdullah, M. A.; Salman, A. K. Molecules 2010, 15, 4784. https://doi.org/10.3390/molecules15074784
  7. Konstantinovic, S. S.; Randovanovic, B. C.; Sovilj, S. P.; Stanojevic, S. J. Serb. Chem. Soc. 2008, 73, 7. https://doi.org/10.2298/JSC0801007K
  8. Gaikwad, S.; Gaikwad, C. J. Chem. Pharm. Res. 2010, 2, 106.
  9. Pingaew, R.; Prachayasittikul, S.; Ruchirawat, S. Molecules 2010, 15, 988. https://doi.org/10.3390/molecules15020988
  10. Khan, S. A.; Yusuf, M. European Journal of Medicinal Chemistry 2009, 44, 2270. https://doi.org/10.1016/j.ejmech.2008.06.008
  11. Yadav, S.; Singh, R. V. Spectrochimica Acta Part A 2011, 78, 298. https://doi.org/10.1016/j.saa.2010.10.010
  12. Akbar, A. M.; Mirza A. H.; Voo, C. W.; Tan, A. L.; Bernhardt, P. V. Polyhedron 2003, 22, 3433. https://doi.org/10.1016/j.poly.2003.08.004
  13. Biyala, M. K.; Fahmi, N.; Singh, R. V. Main Group Met. Chem. 2004, 27, 181.
  14. Sireesha, B.; Devi, S.; Refeez, M.; Ram Reddy, M. G. J. Indian Chem. Soc. 1999, 76, 498.
  15. Yadav, L. D. S.; Singh, S. Indian J. Chem. 2001, 40 B, 440.
  16. Riopedre, G. G.; Garc a, M. I. F.; Noya, A. M. G.; Fernandez, M. A. V.; Bermejo, M. R.; Maneiro, M. Phys. Chem. Chem. Phys. 2011, 13, 18069. https://doi.org/10.1039/c1cp21154d
  17. Nigam, S.; Patel, M. M.; Ray, A. Journal of Physics and Chemistry of Solids 2000, 61, 1389. https://doi.org/10.1016/S0022-3697(00)00025-1
  18. Kasuga, N. C.; Sekino, K.; Koumo, C. J. Inog. Biochem. 2001, 84, 55. https://doi.org/10.1016/S0162-0134(00)00221-X
  19. Reddy, D. N.; Reddy, K. V. Momona Ethiopian Journal of Science 2012, 4, 70.
  20. Karthikeyan, J.; Parameshwara, P.; Shetty, A. N. Environ. Monit. Assess 2011, 173, 569. https://doi.org/10.1007/s10661-010-1405-8
  21. Nanda, K. K.; Das, R.; Venkatsubramanian, K. Dalton. Trans. 1993, 2515.
  22. Biyala, M. K.; Fahmi, N.; Singh, R. V. Main Group Met. Chem. 2004, 27, 3.
  23. Jadon, S. C. S.; Fahmi, N.; Singh, R. V. Synth. React. Inorg. Met. Chem. 1995, 25, 1345. https://doi.org/10.1080/15533179508014679
  24. Garg, R.; Saini, M. K.; Fahmi, N.; Singh, R. V. Indian J. Chem. 2005, 44A, 2433.
  25. Biyala, M. K.; Fahmi, N.; Singh, R. V. Indian J. Chem 2004, 43A, 1662.
  26. Sharma, K.; Joshi, S. C.; Singh, R. V. Metal Based Drug 2000, 7, 105. https://doi.org/10.1155/MBD.2000.105
  27. Garg, R.; Fahmi, N.; Singh, R. V. Russian J. Coord. Chem. 2008, 34, 198. https://doi.org/10.1134/S1070328408030093
  28. Garg, R.; Saini, M. K.; Fahmi, N.; Singh, R. V. Trans. Met. Chem. 2006, 31, 362. https://doi.org/10.1007/s11243-005-0001-1
  29. Saxena, C.; Bhardwaj, N. C.; Singh, D.; Singh, R. V. Synth. React. Inorg. Met. Org. Chem. 1993, 23, 1391. https://doi.org/10.1080/15533179308016694
  30. Tweedy, B. G. Phytopathology 1964, 55, 910.
  31. Mohamad, G. G.; Omar, M. M.; Hindy, A. M. M. Spectrochimica Acta Part A 2005, 62, 1140. https://doi.org/10.1016/j.saa.2005.03.031
  32. Cooper, R. L.; Goldman, J. M.; Stoper, T. E. Toxicol. Indus. Health 1999, 15, 25.
  33. Dave, S.; Chaudhary, A.; Agarwal, M.; Joshi, S. C.; Singh, R. V. Indian J. Chem. 2003, 42A, 268.