소아 청소년 양극성장애 환아군에서의 첫 기분 삽화의 극성에 따른 단기 예후 비교 : 단일 기관 연구

The Comparison of the Short-Term Prognosis According to the Polarity of First Episode in Children and Adolescent with Bipolar Disorder : A Single Center Study

  • 권국주 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 박수빈 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 이수민 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 김재원 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 신민섭 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 유희정 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 조수철 (서울대학교병원 어린이병원 소아청소년정신건강의학과) ;
  • 김붕년 (서울대학교병원 어린이병원 소아청소년정신건강의학과)
  • Kweon, Kukju (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Park, Subin (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Lee, Soo-Min (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Kim, Jae-Won (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Shin, Min-Sup (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Yoo, Hee-Jeong (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Cho, Soo-Churl (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital) ;
  • Kim, Bung-Nyun (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital)
  • 투고 : 2013.08.02
  • 심사 : 2013.09.29
  • 발행 : 2013.10.31

초록

Objectives : This study was conducted to evaluate the association between first episode polarity of pediatric bipolar disorder and prognosis. Methods : We analyzed the clinical records of 66 inpatient subjects with DSM-IV defined pediatric bipolar disorder. The patients were split into 2 groups according to the polarity of the illness onset [depressive onset (DO) vs. manic/hypomanic/mixed onset (MO)]. Clinical feature and prognosis were compared between the two groups of patients. Results : In our sample, 68% of patients experienced a depressive onset. In DO patients, rates of suicidal attempt, episodic illness course and comorbid disruptive behavior disorder were higher than rates in MO patients. Conclusion : Findings from this study suggest that polarity of illness onset may be useful in predicting the prognosis of pediatric bipolar disorder.

키워드

참고문헌

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