Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
권호 표지

Clinical and Physical Characteristics That Affect Apnea-Hypopnea Index in Suspected Obstructive Sleep Apnea Patients : The Preliminary Study

폐쇄성수면무호흡증 의심환자에서 무호흡저호흡지수에 영향을 주는 임상적 신체적 요인 : 예비연구

  • Kang, Seung-Gul (Department of Psychiatry, Gil Medical Center, Gachon University School of Medicine) ;
  • Shin, Seung-Heon (Department of Otorhinolaryngology, School of Medicine, Catholic University of Daegu) ;
  • Lee, Yu Jin (Department of Psychiatry, Gil Medical Center, Gachon University School of Medicine) ;
  • Jung, Joo Hyun (Department of Otolaryngology, Gil Medical Center, Gachon University School of Medicine) ;
  • Kang, Il Gyu (Department of Otolaryngology, Gil Medical Center, Gachon University School of Medicine) ;
  • Park, Insook (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Catholic University of Daegu School of Medicine) ;
  • Kim, Peter Chanwoo (EFIL Plastic Clinic) ;
  • Ye, Mi Kyung (Department of Otorhinolaryngology, School of Medicine, Catholic University of Daegu) ;
  • Hwang, Hee Young (Department of Radiology, Gil Medical Center, Gachon University School of Medicine) ;
  • Kim, Seon Tae (Department of Otolaryngology, Gil Medical Center, Gachon University School of Medicine) ;
  • Park, Kee Hyung (Department of Neurology, Gil Medical Center, Gachon University School of Medicine) ;
  • Kim, Ji-Eun (Department of Neurology, Catholic University of Daegu School of Medicine)
  • 강승걸 (가천대학교 의학전문대학원 길병원 정신건강의학교실) ;
  • 신승헌 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 이유진 (가천대학교 의학전문대학원 길병원 정신건강의학교실) ;
  • 정주현 (가천대학교 의학전문대학원 길병원 이비인후과학교실) ;
  • 강일규 (가천대학교 의학전문대학원 길병원 이비인후과학교실) ;
  • 박인숙 (대구가톨릭대학교 의과대학 치과학교실 구강악안면외과) ;
  • 김찬우 (에필성형외과) ;
  • 예미경 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 황희영 (가천대학교 의학전문대학원 길병원 영상의학과학교실) ;
  • 김선태 (가천대학교 의학전문대학원 길병원 이비인후과학교실) ;
  • 박기형 (가천대학교 의학전문대학원 길병원 신경과학교실) ;
  • 김지언 (대구가톨릭대학교 의과대학 신경과학교실)
  • Received : 2013.03.29
  • Accepted : 2013.05.13
  • Published : 2013.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives The purpose of this study is to find the influential clinical and physical characteristics which affect apnea-hypopnea index (AHI) in suspected obstructive sleep apnea (OSA) patients. Methods We evaluated the comprehensive factors including sleep related symptoms, clinical scales, medical history, substance use, and anthropometric data of the 119 participants who complained of the symptoms of OSA. All the participants underwent attended-full night laboratory polysomnography. The correlation and multiple regression analysis were conducted to find the influential and predictive factors of AHI. Results A multiple linear regression model 1 showed that higher AHI was associated with higher body mass index (BMI)(p < 0.001) and higher frequency of observed apnea (p = 0.002). In multiple linear regression model 2, AHI was associated with higher BMI (p < 0.001) and loudness of snoring (p = 0.018). Conclusions The present preliminary results suggest that BMI and observed apnea are most influential factors that affect AHI in suspected OSA patients. In the future study we will design the prediction formula for the OSA and AHI, which is useful in the clinical medical field.

Keywords

References

  1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-1235. https://doi.org/10.1056/NEJM199304293281704
  2. Bearpark H, Elliott L, Grunstein R, Cullen S, Schneider H, Althaus W, et al. Snoring and sleep apnea. A population study in Australian men. Am J Respir Crit Care Med 1995;151:1459-1465. https://doi.org/10.1164/ajrccm.151.5.7735600
  3. Kim J, In K, Kim J, You S, Kang K, Shim J, et al. Prevalence of sleepdisordered breathing in middle-aged Korean men and women. Am J Respir Crit Care Med 2004;170:1108-1113. https://doi.org/10.1164/rccm.200404-519OC
  4. Young T, Evans L, Finn L, Palta M. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women. Sleep 1997;20:705-706.
  5. Sun LM, Chiu HW, Chuang CY, Liu L. A prediction model based on an artificial intelligence system for moderate to severe obstructive sleep apnea. Sleep Breath 2011;15:317-323. https://doi.org/10.1007/s11325-010-0384-x
  6. Seo WS, Son HI, Koo BH, Lee KH, Song CJ, Kwak KP, et al. Clinical features of Korean obstructive sleep apnea syndrome and usefulness of Korean version of epworth sleepiness scale. J Korean Soc Biol Ther Psychiatry 2005;11:150-157.
  7. Cho YW, Lee JH, Son HK, Lee SH, Shin C, Johns MW. The reliability and validity of the Korean version of the Epworth sleepiness scale. Sleep Breath 2011;15:377-384. https://doi.org/10.1007/s11325-010-0343-6
  8. Kwon C, Shin SY, Lee KH, Cho JS, Kim SW. Usefulness of Berlin and STOP questionnaires as a screening test for sleep apnea in Korea. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:768-772. https://doi.org/10.3342/kjorl-hns.2010.53.12.768
  9. Kong HW, Lee HJ, Choi YS, Rha JH, Ha CK, Hwang DU, et al. Clinical predictors of obstructive sleep apnea. J Korean Neurol Assoc 2005;23:324-329.
  10. Li KK, Kushida C, Powell NB, Riley RW, Guilleminault C. Obstructive sleep apnea syndrome: a comparison between Far-East Asian and white men. Laryngoscope 2000;110(10 Pt 1):1689-1693. https://doi.org/10.1097/00005537-200010000-00022
  11. Klem GH, Lüders HO, Jasper HH, Elger C. The ten-twenty electrode system of the International Federation. The International Federation of Clinical Neurophysiology. Electroencephalogr Clin Neurophysiol Suppl 1999;52:3-6.
  12. Iber C, Ancoli-Israel S, Chesson AL Jr, Quan SF. The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. Westchester, IL: American Academy of Sleep Medicine;2007.
  13. Caffo B, Diener-West M, Punjabi NM, Samet J. A novel approach to prediction of mild obstructive sleep disordered breathing in a population- based sample: the Sleep Heart Health Study. Sleep 2010;33: 1641-1648. https://doi.org/10.1093/sleep/33.12.1641
  14. Musman S, Passos VM, Silva IB, Barreto SM. Evaluation of a prediction model for sleep apnea in patients submitted to polysomnography. J Bras Pneumol 2011;37:75-84. https://doi.org/10.1590/S1806-37132011000100012
  15. Bouloukaki I, Kapsimalis F, Mermigkis C, Kryger M, Tzanakis N, Panagou P, et al. Prediction of obstructive sleep apnea syndrome in a large Greek population. Sleep Breath 2011;15:657-664. https://doi.org/10.1007/s11325-010-0416-6