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Survey of Willingness to Accept Chemotherapy among Elderly Malaysian Patients

  • Razali, Rizah Mazzuin (Medical Department, Faculty of Medicine, University of Malaya) ;
  • Bee, Ping Chong (Medical Department, Faculty of Medicine, University of Malaya) ;
  • Gan, Gin Gin (Medical Department, Faculty of Medicine, University of Malaya)
  • Published : 2013.03.30

Abstract

Background: The geriatric population in Malaysia is predicted to increase from 4% of the total population in 1998 to 9.8% by 2020, in parallel with developments in the socioeconomy. Cancer is expected to be a major medical issue among this population. However, the decision for treatment in Malaysia is always decided by the caregivers instead of the elderly patients themselves. Objective: The aim of the study was to assess the willingness to accept chemotherapy among elderly Malaysians. Materials and Methods: In this cross-sectional study, patients aged 60 and above from various clinics/wards were recruited. Those giving consent were interviewed using a questionnaire. Results: A total of 75 patients were recruited, 35 patients (47%) with a history of cancer. The median age was 73 years old. There were 29 Chinese (38.7%), 22 Indian (29.3%), 20 Malay (26.7%) and four other ethnicity patients. Some 83% and 73% of patients willing to accept strong and mild chemotherapy, respectively. Patients with cancer were more willing to accept strong and mild chemotherapy compared to the non-cancer group (88.6% vs 62.5%, P=0.005, 94% vs 80%, P=0.068). On sub-analysis, 71.4% and 42.9% of Chinese patients without a history of cancer were not willing to receive strong and mild chemotherapy, respectively. Conclusions: The majority of elderly patients in UMMC were willing to receive chemotherapy if they had cancer. Experience with previous treatment had positive influence on the willingness to undergo chemotherapy.

Keywords

References

  1. Berrino F, Capoccaccia R, Esteve J, Gatta G (1999). Survival of cancer patients in Europe: The EUROCARE-2 Study. IARC Sci Publ, 151, 1-572.
  2. Biganzoli L, Aapro M (2003). Adjuvant chemotherapy in the elderly. Ann Oncol, 14, 1-3. https://doi.org/10.1093/annonc/mdg035
  3. Denice E, Arti H, Marcia G (2012). Integrating a cancer-specific geriatric assessment into survivorship care. Clin J of Oncol Nurs, 16, 78-85. https://doi.org/10.1188/12.CJON.E78-E83
  4. Doyle C, Crump M, Pintilie M, et al (2001). Does palliative chemotherapy palliate? Evaluation of expectations, outcomes, and cost in women receiving chemotherapy for advanced ovarian cancer. J Clin Oncol, 19,1266-74.
  5. Extermann M, Albran G, Chen H, et al (2003). Are older French patients as willing as older American patients to undertake chemotherapy? J Clin Oncol, 21, 3214-9. https://doi.org/10.1200/JCO.2003.08.091
  6. Folprecht G, Cunningham D, Ross P, et al (2004). Efficacy of 5-fluorouracil-based chemotherapy in elderly patients with metastatic colorectal cancer: a pooled analysis of clinical trials. Ann Oncol, 15, 1330-8 https://doi.org/10.1093/annonc/mdh344
  7. Kahn KL, Adams JL, Weeks JC, et al (2010). Adjuvant chemotherapy use and adverse events among older patients with stage III colon cancer. JAMA, 303, 1037-45. https://doi.org/10.1001/jama.2010.272
  8. Kow AW, Sadayan NA, Emest A, et al (2012). Is pancreaticoduodenectomy justified in elderly patients? Surgeon, 10, 128-36. https://doi.org/10.1016/j.surge.2011.02.005
  9. Lam YC, Cheng CW, Peng H, et al (2009). Cancer patients' attitude towards Chinese medicine: a Hong Kong survey. Chinese Medicine, 4, 25 https://doi.org/10.1186/1749-8546-4-25
  10. Lee PR (1980). Perceptions and uses of Chinese medicine among the Chinese in Hong Kong. Culture, Medicine and Psychiatry, 4, 345-75. https://doi.org/10.1007/BF00051811
  11. Lichtman SM (2003). Guidelines for the Treatment of Elderly Cancer Patients. Cancer Control, 10, 445-53.
  12. Lim GC (2002). Overview of Cancer in Malaysia. Jpn J Clin Oncol, 32, 37-42. https://doi.org/10.1093/jjco/hye132
  13. Liu TG, Xiong SQ, Yan Y, Zhu H, Yi C (2012). Use of Chinese herb medicine in cancer patients: a survey in Southwestern China. Evid Based Complement Alternat Med, 2012, 769042.
  14. Lodovico Balducci (2003). New paradigms for treating elderly patients with cancer: the comprehensive geriatric assessment and guidelines for supportive care. J Support Oncol, 1, 30-7.
  15. Loh CH (2009). Use of traditional chinese medicine in Singapore children: perceptions of parents and paediatricians. Sing Med J, 50, 1162-7.
  16. Papamichael D, Audisio R, Horiot JC, et al (2009). Treatment of the elderly colorectal cancer patient: SIOG expert recommendations. Ann Oncol, 20, 5-16.
  17. Papamichael D, Audisio R, Horiot JC, et al (2009). Treatment of the elderly colorectal cancer patient: SIOG expert recommendations. Ann Oncol, 20, 5-16.
  18. Peake MD, Thompson S, Lowe D, et al (2003). Ageism in the management of lung cancer. Age Ageing, 32, 171-7. https://doi.org/10.1093/ageing/32.2.171
  19. Quoix E (2012). Therapeutic options in older patients with metastatic non-small cell lung cancer. Ther adv Med Oncol, 4, 247-54. https://doi.org/10.1177/1758834012455838
  20. Schuurmans H, Steverink N, Lindenberg S, Frieswijk N (2004). Slaets, old or frail:what tells us more. J Gerontol Series A Biol Sci Med Sci, 59, 962-5. https://doi.org/10.1093/gerona/59.9.M962
  21. Second Report of the National Cancer Registry Cancer Incidence In Malaysia 2003. http://www.radiologymalaysia.org/Archive/NCR/2ndNCR.pdf
  22. Slevin ML, Stubbs L, Plant HJ, et al (1990). Attitudes to chemotherapy: Comparing views of patients with cancer with those of doctors, nurses, and general public. BMJ, 300, 1458-60. https://doi.org/10.1136/bmj.300.6737.1458
  23. Soubeyran P, Fonck M, Blanc-Bisson C, et al (2012). Predictors of early death in older patients treated with first-line chemotherapy for cancer. J Clin Oncol, 30, 1829-34. https://doi.org/10.1200/JCO.2011.35.7442
  24. Spina M, Balzarotti M, Uziel L, et al (2012). Modulated chemotherapy according to modified comprehensive geriatric assessment in 100 consecutive elderly patients with diffuse large B-cell lymphoma. Oncologist, 17, 838-46. https://doi.org/10.1634/theoncologist.2011-0417
  25. Surbone A, Kagawa-Singer M, Terret C, et al (2007). The illness trajectory of elderly cancer patients across cultures: SIOG position paper. Ann Oncol, 18, 633-8.

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