Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Comparison of Ovariectomy and Ovariohysterectomy in Terms of Postoperative Pain Behavior and Surgical Stress in Dogs

개에서 난소자궁절제술과 난소절제술 후 나타나는 통증 행동과 스트레스 반응의 비교

  • Lee, Scott-S. (Banfield Pet Hospital) ;
  • Lee, Seung-Yong (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Park, Se-Jin (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Kim, Young-Ki (Haeundae Animal Medical Center) ;
  • Seok, Seong-Hoon (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Hwang, Jae-Min (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Lab. of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Yeon, Seong-Chan (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University)
  • 이스캇 ;
  • 이승용 (경상대학교 수의과대학 수의외과.행동학 연구실) ;
  • 박세진 (경상대학교 수의과대학 수의외과.행동학 연구실) ;
  • 김영기 (해운대 동물메디컬센터) ;
  • 석성훈 (경상대학교 수의과대학 수의외과.행동학 연구실) ;
  • 황재민 (경상대학교 수의과대학 수의외과.행동학 연구실) ;
  • 이희천 (경상대학교 수의과대학 수의영상의학 실험실) ;
  • 연성찬 (경상대학교 수의과대학 수의외과.행동학 연구실)
  • Accepted : 2013.06.21
  • Published : 2013.06.30
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Abstract

This study was conducted to evaluate the clinical relevance and effectiveness of ovariectomy (OVE) and ovariohysterectomy (OVH) in terms of postoperative pain behavior and surgical stress. Thirteen healthy intact mongrel purpose-bred female dogs were used in this study. OVE was performed in six dogs whereas OVH was performed in seven dogs. Prior to, 1, 2, 4, 6, 12, and 24 h after surgery, pain assessment was performed by using the Short form of Composite Measure Pain Scale (CMPS-SF) and blood analysis for the determination of glucose, creatine kinase (CK), and cortisol were done. Also, surgical time, duration of anesthesia, and incision length were compared between two groups. As a result, OVH group as opposed to OVE group showed significantly longer in surgical time, duration of anesthesia, and incision length. Also, based on the two-way ANOVA test, the CMPS-SF had significant differences (p < 0.05) between two groups, with the OVE dogs having lower values at 1, 2, 4, and 6 h postoperatively. In addition, in terms of CK, the value at 1, 2, 4, 6, and 12 h were significantly (p < 0.05) increased from the baseline value for the OVH group. However, as for CK in OVE group, the values at 4, 6, and 12 h were significantly increased from the baseline value. As for blood glucose, a significant (p < 0.05) increase from the baseline was shown at 1 h postoperatively in OVH group and no significant increase was shown in OVE group. In terms of serum cortisol level, the values at the 1 and 2 h were significantly (p < 0.05) increased from the baseline value for both groups. In conclusion, our study has shown that OVE can be considered as a superior choice in terms of sterilization technique in female dogs, considering shorter incision length, surgical time, duration of anesthesia along with lower pain and surgical stress response than OVH.

본 연구는 개에서 난소자궁절제술과 난소절제술의 실시가 동물의 통증행동과 스트레스에 미치는 영향을 비교하고, 임상적용 가능성을 평가하기 위하여 실시되었다. 13 마리의 건강한 암컷 중 (4.2-5.5 kg) 6 마리의 개에서 난소절제술이 행하여졌고, 7 마리에서 난소자궁절제술이 이루어졌다. 술 후 두 그룹 간에 수술 시간, 마취 시간, 복벽의 절개 길이를 비교하였다. 또한 술 전과 술 후 1, 2, 4, 6, 12, 24 시간째에 Short form of composite measure pain scale (CMPS-SF) 를 사용하여 통증 점수를 측정하였고 혈중 glucose 와 creatine kinase 그리고 cortisol 수치를 측정하였다. 난소자궁절제술을 시행한 그룹에서는 난소절제술을 시행한 그룹에 비해 유의적으로 (p < 0.05) 긴 수술 시간, 마취 시간, 복벽 절개 길이를 나타내었다. Two-way ANOVA test 결과 CMPS-SF에 의한 통증점수가 두 그룹 간에 유의적 (p < 0.05) 차이를 보였으며 술 후 1, 2, 4, 6 시간째 난소절제술을 행한 그룹에서 유의적으로 낮은 수치를 나타내었다. Glucose 의 경우 난소자궁절제술을 행한 그룹에서는 술 전과 비교해 유의적 (p < 0.05) 농도 증가가 술 후 1 시간째에 나타났으나 난소절제술을 행한 그룹에서는 술 후 전체 관찰기간 동안 유의적 농도 증가가 관찰 되지 않았다. Creatine Kinase 의 경우 난소자궁절제술을 행한 그룹에서는 술 전과 비교하여 술 후 1, 2, 4, 6, 12 시간째에 유의적 (p < 0.05) 농도 증가를 나타내었으나 난소절제술 그룹의 경우 술 후 4, 6, 12 시간째에만 술 전과 비교하여 유의적 (p < 0.05) 농도 증가를 나타내었다. Cortisol 의 경우 두 그룹 모두 술 후 1, 2 시간째에 유의적인 (p < 0.05) 농도 상승을 나타내었다. 본 연구 결과 난소절제술을 이용한 암캐의 중성화 수술 방법은 난소자궁절제술에 비해 짧은 복벽 절개, 수술 시간, 마취 시간을 요하며, 적은 술 후 통증과 스트레스를 유발하므로 난소절제술을 시행하는 것이 환자에게 바람직할 것으로 판단된다.

Keywords

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