DOI QR코드

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DEVICE CLOSURE OF A LARGE ATRIAL SEPTAL DEFECT IN A PATIENT WITH SEVERE PULMONARY ARTERIAL HYPERTENSION AFTER 1 YEAR USE OF AN ORAL ENDOTHELIN RECEPTOR ANTAGONIST

  • Jung, In Hyun (Department of Internal Medicine, Sejong General Hospital) ;
  • Lee, Sang Yun (Department of Pediatrics, Sejong General Hospital) ;
  • Lee, Sook Jin (Department of Internal Medicine, Sejong General Hospital) ;
  • Lee, Joo Young (Department of Internal Medicine, Sejong General Hospital) ;
  • Park, Nam Jin (Department of Internal Medicine, Sejong General Hospital) ;
  • Ahn, Dea Sung (Department of Internal Medicine, Sejong General Hospital) ;
  • Jung, Jae Hoon (Department of Internal Medicine, Sejong General Hospital) ;
  • Shin, Dong Hee (Department of Internal Medicine, Sejong General Hospital) ;
  • Lim, Dal Soo (Department of Internal Medicine, Sejong General Hospital)
  • Received : 2013.04.01
  • Accepted : 2013.08.12
  • Published : 2013.09.27

Abstract

The presence of severe pulmonary arterial hypertension (PAH) in patients with atrial septal defect (ASD) is still thought to preclude shunt closure, although there are several reports of good clinical outcomes after vasodilator therapy. We report the case of a young woman with ASD and severe PAH who was able to successfully undergo percutaneous shunt closure following 1 year use of the oral endothelin receptor antagonist, bosentan.

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  1. Targeted Therapy Is Required for Management of Pulmonary Arterial Hypertension After Defect Closure in Adult Patients With Atrial Septal Defect and Associated Pulmonary Arterial Hypertension vol.56, pp.1, 2013, https://doi.org/10.1536/ihj.14-183
  2. Large Atrial Septal Defect Closure in a Patient with Severe Pulmonary Arterial Hypertension vol.50, pp.5, 2013, https://doi.org/10.5090/kjtcs.2017.50.5.378
  3. “Treat and repair” strategy for shunt lesions: a critical review vol.10, pp.2, 2020, https://doi.org/10.1177/2045894020917885