Asian Pacific Journal of Cancer Prevention

  • 제14권4호
  • /
  • Pages.2541-2544
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  • 2013
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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For Which Cancer Types can Neuron-Specific Enolase be Clinically Helpful in Turkish Patients?

  • 발행 : 2013.04.30
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초록

Background: The aim of the present study was to evaluate the serum neuron-specific enolase (NSE) levels in patients with prostate cancer, Hodgkin lymphoma, lung cancer and peripheral nerve tumors. Materials and Methods: NSE levels were determined by ELISA in the sera of 100 prostate cancer, 47 Hodgkin lymphoma, 35 lung cancer and 35 peripheral nerve tumor patients and also in 132 healthy controls. Results: The median levels of serum NSE were elevated in patients with lung cancer (p=0.018) and peripheral nerve tumors (p=0.008). NSE levels in prostate cancer and Hodgkin lymphoma patients were higher than the controls but there was no statistically significant difference (p>0.05). Conclusions: We conclude that NSE may be applied in routine to gain insight about the clinical statuses of various cancer patients, but more studies are needed to determine the organ specificity.

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참고문헌

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피인용 문헌

  1. Clinical Observations on the Association Between Diagnosis of Lung Cancer and Serum Tumor Markers in Combination vol.14, pp.7, 2013, https://doi.org/10.7314/APJCP.2013.14.7.4369
  2. The role of serum neuron-specific enolase in patients with prostate cancer: a systematic review of the recent literature vol.33, pp.1, 2018, https://doi.org/10.5301/ijbm.5000286