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Review on RCT Research Papers Related Nausea and Vomiting in Pregnancy - Focusing on Acupoint Treatment -

임신오조(姙娠惡阻) 관련 무작위대조군연구(RCT)에 관한 고찰 - 경혈을 이용한 치료를 중심으로 -

  • Jang, Suk-Woo (Dept. of OB & GY, Dong-Guk University Ilsan Oriental Hospital) ;
  • Ahn, In-Suk (Dept. of OB & GY, Dong-Guk University Ilsan Oriental Hospital) ;
  • Choi, Min-Sun (Dept. of OB & GY, Dong-Guk University Ilsan Oriental Hospital) ;
  • Kim, Dong-Il (Dept. of OB & GY, Dong-Guk University Ilsan Oriental Hospital)
  • 장석우 (동국대학교 일산한방병원 한방여성의학과) ;
  • 안인숙 (동국대학교 일산한방병원 한방여성의학과) ;
  • 최민선 (동국대학교 일산한방병원 한방여성의학과) ;
  • 김동일 (동국대학교 일산한방병원 한방여성의학과)
  • Received : 2013.04.25
  • Accepted : 2013.05.09
  • Published : 2013.05.31

Abstract

Objectives: To observe randomized controlled trials(RCTs) related to investigating the effects of acupoint treatments on nausea and vomiting in pregnancy to establish the basis of korean medical treatments, and suggest the problems of future clinical research. Methods: After searching for national and international papers published after 2000 and restricting the parameters to 'clinical trial', 'controlled clinical trial', 'randomized controlled trial', then comparing the subjects, methods, research tools, and results to understand the effects and re-comparing the conflicting results to assume the cause. Results: Of the 9 research papers that applied acupressure, four of them used control and experimental groups, and three(75%) research papers indicated significant reduction in vomiting and nausea, and of the seven research papers that utilized the experimental and placebo groups, five(71.4%) reported significant reducing effects. Of the four research papers the used acupuncture treatments, four research papers using control and placebo groups, two showed improvements in symptoms but did not have significant results compared to sham acupuncture groups, and two showed significant reduction of symptoms compared to the control groups. The one research paper that used electrical stimulation showed significant results in the reduction of vomiting and nausea compared to the control group. Conclusions: Acupressure and electrical stimulation showed efficacy reducing the symptoms. Acupuncture treatments did not indicate efficacy some experiments. Therefore it is thought that future acupuncture treatments should use methods that resemble actual clinical medicine to establish efficacy to produce significant results.

Keywords

References

  1. 황병철, 김석영. 임신오조에서 항구토 제의 효과. 대한산부회지. 2010;53(1): 15-22.
  2. 옥진유 등. 임신오조환자 임상보고 1 례. 대한한방부인과학회지. 2012;25(1): 116-24.
  3. Fell DB, et. al. Risk factors for hyperemesis gravidarum requiring hospital admission during pregnancy. Obstet Gynecol. 2006;107(2Pt1):277-284. https://doi.org/10.1097/01.AOG.0000195059.82029.74
  4. Gadsby R, et. al. A prospective study of nausea and vomiting during pregnancy. Br J Gen Pract. 1993;43:245-248.
  5. Vellacott ID, et. al. Nausea and vomiting in early pregnancy. In J Gynaecol Obstet. 1988;27:57-62.
  6. Lo WY, Friedman JM. Teratogenicity of recently introduced medications in human regnancy. Obstet Gynecol. 2002; 100:465-473. https://doi.org/10.1016/S0029-7844(02)02122-1
  7. Matok I, et. al. The safety of metoclopramide use in the first trimester of pregnancy. N Engl J Med. 2009;360:2528-2535. https://doi.org/10.1056/NEJMoa0807154
  8. Habek D, et al. Success of acupuncture and acupressure of the PC6 acupoint in the treatment of hyperemesis gravidarum. Forsch Komplementarmed Klass Naturheilkd. 2004;11:20-23. https://doi.org/10.1159/000077192
  9. Shin HS, et. al. Effect of Nei-Guan point(P6) acupressure on ketonuria levels, nausea and vomiting in women with hyperemesis gravidarum. J Adv Nurs. 2007;59(5):510-519. https://doi.org/10.1111/j.1365-2648.2007.04342.x
  10. Puangsricharern A, Mahasukhon S. Effectiveness of Auricular Acupressure in the Treatment of Nausea and Vomiting in Early Pregnancy. J Med Assoc Thai. 2008;91(11):1633-1638.
  11. Norheim AJ, et. al. Acupressure treatment of morning sickness in pregnancy. A randomised, double-blind, placebocontrolled study. Scand J Prim Health Care. 2001;19(1):43-47. https://doi.org/10.1080/02813430120819
  12. Steele NM, et. al. Effect of acupressure by Sea-Bands on nausea and vomiting of pregnancy. J Obstet Gynecol Neonatal Nurs. 2001;30(1):61-70. https://doi.org/10.1111/j.1552-6909.2001.tb01522.x
  13. Werntoft E, Dykes AK. Effect of acupressure on nausea and vomiting during pregnancy. A randomized, placebo-controlled, pilot study. J Reprod Med. 2001;46(9):835-839.
  14. Heazell A, et. al. Acupressure for the in-patient treatment of nausea and vomiting in early pregnancy: a randomized control trial. Am J Obstet Gynecol. 2006;194(3):815-820. https://doi.org/10.1016/j.ajog.2005.08.042
  15. Jamigorn M, Phupong V. Acupressure and vitamin B6 to relieve nausea and vomiting in pregnancy: a randomized study. Arch Gynecol Obstet. 2007; 276(3):245-249. https://doi.org/10.1007/s00404-007-0336-2
  16. Can Gürkan O, Arslan H. Effect of acupressure on nausea and vomiting during pregnancy. Complement Ther Clin Pract. 2008;14(1):46-52. https://doi.org/10.1016/j.ctcp.2007.07.002
  17. Carlsson CP, et. al. Manual acupuncture reduces hyperemesis gravidarum: a placebo-controlled randomized, singleblind, crossover study. J Pain Symptom Manage. 2000;20(4):273-279. https://doi.org/10.1016/S0885-3924(00)00185-8
  18. Knight B, et. al. Effect of acupuncture on nausea of pregnancy: a randomized, controlled trial. Obstet Gynecol. 2001; 97(2):184-188. https://doi.org/10.1016/S0029-7844(00)01152-2
  19. Smith C, Crowther C, Beilby J. Acupuncture to treat nausea and vomiting in early pregnancy: a randomized controlled trial. Birth. 2002;29(1):1-9. https://doi.org/10.1046/j.1523-536X.2002.00149.x
  20. Rosen T, et. al. A randomized controlled trial of nerve stimulation for relief of nausea and vomiting in pregnancy. Obstet Gynecol. 2003;102(1):129-135. https://doi.org/10.1016/S0029-7844(03)00375-2
  21. Dundee JW, et. al. Traditional Chinese acupuncture: a potentially useful antiemetic? Br Med J. 1986;293(6):583 https://doi.org/10.1136/bmj.293.6547.583
  22. Streitberger K, et. al.. Acupuncture for nausea and vomiting: an update of clinical and experimental studies. Auton Neurosci. 2006;129(1-2):107-117. https://doi.org/10.1016/j.autneu.2006.07.015
  23. Rebecca JH, et. al. Meta-analysis of acustimulation effects on nausea and vomiting in pregnant women. Explore (NY). 2006;2(5):412-421. https://doi.org/10.1016/j.explore.2006.06.002

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