Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Plasma Medicine: How can Nonthermal Atmospheric Plasma be Applied to Medicine?

플라즈마 메디신: 저온 상압 플라즈마는 어떻게 의학분야에 적용될 수 있는가?

  • Park, Sang Rye (Department of Oral Anatomy, School of Dentistry, Pusan National University) ;
  • Hong, Jin Woo (Department of Korean Internal Medicine, School of Korean Medicine, Pusan National University) ;
  • Lee, Hae June (Department of Electronics Engineering, Pusan National University) ;
  • Kim, Gyoo Cheon (Department of Oral Anatomy, School of Dentistry, Pusan National University)
  • 박상례 (부산대학교 치의학 전문대학원 구강해부학 교실) ;
  • 홍진우 (부산대학교 한의학 전문대학원) ;
  • 이해준 (부산대학교 전자전기공학부) ;
  • 김규천 (부산대학교 치의학 전문대학원 구강해부학 교실)
  • Received : 2013.06.05
  • Accepted : 2013.06.24
  • Published : 2013.06.30
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Abstract

As a forth state of material, plasma is ionized gas, which generates characteristically various reactive species. After late of $20^{th}$ century, plasma has been widely used in industry. After nonthermal atmospheric plasma was developed, it has been applied to biomedical fields. Nonthermal atmospheric plasma does not give thermal damages to human tissues, and it shows the high efficiency in cancer treatment, sterilization, tooth bleaching, coagulation, and wound healing. Because the application of plasma to biomedicine has been expanded through interdisciplinary studies, its value of high medical technology is increasing now. Since nonthermal atmospheric plasma was first applied to the mammalian cells and microorganisms, many valuable studies has been performed for about last 10 years, so that now the new research area called 'plasma medicine' has been formed. This article introduces the recent data resulted from plasma medicine and helps to understand the plasma medicine.

플라즈마는 물질의 제4의 상태로서 이온화된 가스로 불리며 다양한 활성종 및 수산화기, 하전입자, 이온, 자유 전자, 산소등을 발생시키는 특징을 가지고 있다. 20세기 후반에 플라즈마는 산업현장에서 활발히 사용되고 있으며, 최근 저온 상압 플라즈마 장치가 개발되면서 의생명 분야에 적용되기 시작했다. 저온 상압 플라즈마는 인체조직에 열 손상을 입히지 않을 뿐만 아니라, 암 치료, 살균, 치아미백, 지혈, 상처치유 등에서 높은 효율성을 보이고 있다. 이때 발생되는 활성종은 포유세포나 병원균에 영향을 미치는 것으로 알려져 있다. 또한, 다학제간의 연구를 통해 저온 상압 플라즈마의 활용범위는 다양한 영역으로 넓어지고 있으며, 새로운 첨단 의료기술로서의 가치가 높아지고 있다. 저온 상압 플라즈마가 포유세포와 미생물에 적용된 이후, 지난 10여 년간 급속한 발전을 통해 최근 플라즈마 메디신이란 학문영역으로 성장했다. 본 논문은 저온 플라즈마가 적용되고 있는 분야에 대해 소개하고, 플라즈마 메디신에 대한 이해를 돕고자 한다.

Keywords

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