Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Screening for diabetes mellitus using gingival crevicular blood with the help of a self-monitoring device

  • Gaikwad, Subodh (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre) ;
  • Jadhav, Varsha (Department of Periodontics, Yogita Dental College and Hospital) ;
  • Gurav, Abhijit (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre) ;
  • Shete, Abhijeet R. (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre) ;
  • Dearda, Hitesh M. (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre)
  • Received : 2012.12.26
  • Accepted : 2013.01.18
  • Published : 2013.02.28
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Abstract

Purpose: The purpose of study was to compare blood glucose in capillary finger-prick blood and gingival crevice blood using a self-monitoring blood glucose device among patients with gingivitis or periodontitis. Methods: Thirty patients with gingivitis or periodontitis and bleeding on probing (BOP) were chosen. The following clinical periodontal parameters were noted: probing depth, BOP, gingival bleeding index, and periodontal disease index. Blood samples were collected from gingival crevicular blood (GCB) and capillary finger-prick blood (CFB). These samples were analyzed using a glucose self-monitoring device. Results: Descriptive statistical analysis has been carried out in the present study. Data were analyzed using a Pearson's correlation coefficient and Student's t-test. A r-value of 0.97 shows very strong correlation between CFB and GCB, which was statistically highly significant (P<0.0001). Conclusions: The authors conclude that GCB may serve as potential source of screening blood glucose during routine periodontal examination in populations with an unknown history of diabetes mellitus.

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References

  1. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53. https://doi.org/10.2337/diacare.27.5.1047
  2. Express Healthcare. Diabetes in India: current status [Internet]. Mumbai: Express Healthcare; c2001 [cited 2012 Feb 16]. Available from: http://healthcare.financialexpress.com/200808/diabetes02.shtml.
  3. Harris MI, Eastman RC. Early detection of undiagnosed diabetes mellitus: a US perspective. Diabetes Metab Res Rev 2000;16:230-6. https://doi.org/10.1002/1520-7560(2000)9999:9999<::AID-DMRR122>3.0.CO;2-W
  4. Glumer C, Yuyun M, Griffin S, Farewell D, Spiegelhalter D, Kinmonth AL, et al. What determines the cost-effectiveness of diabetes screening? Diabetologia 2006;49:1536-44. https://doi.org/10.1007/s00125-006-0248-x
  5. Ward S, Simpson E, Davis S, Hind D, Rees A, Wilkinson A. Taxanes for the adjuvant treatment of early breast cancer: systematic review and economic evaluation. Health Technol Assess 2007;11:1-144.
  6. Wee LE, Koh GC. The effect of neighborhood, socioeconomic status and a community-based program on multi-disease health screening in an Asian population: a controlled intervention study. Prev Med 2011;53:64-9. https://doi.org/10.1016/j.ypmed.2011.05.005
  7. Grossi SG, Genco RJ. Periodontal disease and diabetes mellitus: a two-way relationship. Ann Periodontol 1998;3:51-61. https://doi.org/10.1902/annals.1998.3.1.51
  8. Mealey BL, Rethman MP. Periodontal disease and diabetes mellitus. Bidirectional relationship. Dent Today 2003; 22:107-13.
  9. Gurav A, Jadhav V. Periodontitis and risk of diabetes mellitus. J Diabetes 2011;3:21-8. https://doi.org/10.1111/j.1753-0407.2010.00098.x
  10. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229-35.
  11. Ramfjord SP. The Periodontal Disease Index (PDI). J Periodontol 1967;38 Suppl:602-10. https://doi.org/10.1902/jop.1967.38.6.602
  12. Parker RC, Rapley JW, Isley W, Spencer P, Killoy WJ. Gingival crevicular blood for assessment of blood glucose in diabetic patients. J Periodontol 1993;64:666-72. https://doi.org/10.1902/jop.1993.64.7.666
  13. American Diabetes Association. Standards of medical care in diabetes: 2007. Diabetes Care 2007;30 Suppl 1:S4-41. https://doi.org/10.2337/dc07-S004
  14. Diabetes India. The Indian task force on diabetes care in India [Internet]. Diabetes India; [cited 2012 Feb 17]. Available from: http://www.diabetesindia.com/diabetes/itfdci.htm.
  15. Loe H. Periodontal disease. The sixth complication of diabetes mellitus. Diabetes Care 1993;16:329-34.
  16. Shetty S, Kohad R, Yeltiwar R, Shetty K. Gingival blood glucose estimation with reagent test strips: a method to detect diabetes in a periodontal population. J Periodontol 2011;82:1548-55. https://doi.org/10.1902/jop.2011.110009
  17. Strauss SM, Wheeler AJ, Russell SL, Brodsky A, Davidson RM, Gluzman R, et al. The potential use of gingival crevicular blood for measuring glucose to screen for diabetes: an examination based on characteristics of the blood collection site. J Periodontol 2009;80:907-14. https://doi.org/10.1902/jop.2009.080542
  18. Sarlati F, Pakmehr E, Khoshru K , Akhondi N. Gingival crevicular blood for assessment of blood glucose levels. J Periodontol Implant Dent 2010;2:17-24.
  19. Parker RC, Rapley JW, Isley W, Spencer P, Killoy WJ. Gingival crevicular blood for assessment of blood glucose in diabetic patients. J Periodontol 1993;64:666-72. https://doi.org/10.1902/jop.1993.64.7.666
  20. Beikler T, Kuczek A, Petersilka G, Flemmig TF. In-dental-office screening for diabetes mellitus using gingival crevicular blood. J Clin Periodontol 2002;29:216-8. https://doi.org/10.1034/j.1600-051x.2002.290306.x
  21. Khader YS, Al-Zubi BN, Judeh A, Rayyan M. Screening for type 2 diabetes mellitus using gingival crevicular blood. Int J Dent Hyg 2006;4:179-82. https://doi.org/10.1111/j.1601-5037.2006.00206.x
  22. Muller HP, Behbehani E. Methods for measuring agreement: glucose levels in gingival crevice blood. Clin Oral Investig 2005;9:65-9. https://doi.org/10.1007/s00784-004-0290-3

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