Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Pulmonary Mucinous Cystadenocarcinoma: Report a Case and Review of CT Findings

  • Choi, Youn Ah (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Ho Yun (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Han, Joungho (Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Joon Young (Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Jhingook (Department of Thoracic & Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kwon, O Jung (Division of Respiratory and Critical Medicine of the Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Kyung Soo (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Published : 2013.04.01
⟨ Previous Next ⟩

Abstract

A pulmonary mucinous cystadenocarcinoma is an extremely rare tumor that is considered to be a cystic variant of mucin-producing lung adenocarcinoma. We present a case of pulmonary mucinous cystadenocarcinoma in a 54-year-old woman. Chest CT scans showed a 4.3-cm-sized, lobulated, well-defined, and homogeneous mass in the right middle lobe with peripheral stippled calcifications that demonstrated low-attenuation with no enhancement after contrast administration; $^{18}F$-fluorodeoxyglucose (FDG) PET/CT demonstrated mild heterogeneous FDG uptake. The mass was diagnosed as adenocarcinoma with mucin production by transbronchial lung biopsy. Right middle lobectomy was performed, and the pathologic examination disclosed a pulmonary mucinous cystadenocarcinoma.

Keywords

References

  1. Chhieng, DC,Fine-needle aspiration cytology of pulmonary mucinous cystadenocarcinoma, Diagn Cytopathol, 36, 1, 581-585(2008) https://doi.org/10.1002/dc.20845
  2. Beasley, MB, Brambilla, E, Travis, WD,The 2004 World Health Organization classification of lung tumors, Semin Roentgenol, 40, 2, 90-97(2005) https://doi.org/10.1053/j.ro.2005.01.001
  3. Tsuta, K, Ishii, G, Nitadori, J, Murata, Y, Kodama, T, Nagai, K,Comparison of the immunophenotypes of signet-ring cell carcinoma, solid adenocarcinoma with mucin production, and mucinous bronchioloalveolar carcinoma of the lung characterized by the presence of cytoplasmic mucin, J Pathol, 209, 3, 78-87(2006) https://doi.org/10.1002/path.1947
  4. Gao, ZH, Urbanski, SJ,The spectrum of pulmonary mucinous cystic neoplasia: a clinicopathologic and immunohistochemical study of ten cases and review of literature, Am J Clin Pathol, 124, 4, 62-70(2005) https://doi.org/10.1309/52XXR6E6U0J2JX0F
  5. Iwasaki, T, Kawahara, K, Nagano, T, Nakagawa, K,Pulmonary mucinous cystadenocarcinoma: an extremely rare tumor presenting as a cystic lesion of the lung, Gen Thorac Cardiovasc Surg, 55, 5, 143-146(2007) https://doi.org/10.1007/s11748-006-0089-z
  6. Sanchez-Carpintero Abad, M, Tamura Ezcurra, MA, de Torres Tajes, JP,Primary pulmonary mucinous cystadenocarcinoma: presentation of a case and a review of the literature, Arch Bronconeumol, 47, 6, 216-217(2011)
  7. Sezer, O, Hoffmeier, A, Bettendorf, O, Franzius, C, Semik, M, Schmid, C,Mucinous cystadenocarcinoma--an extremely rare tumor in a young patient, Thorac Cardiovasc Surg, 54, 7, 216-217(2006) https://doi.org/10.1055/s-2005-872950
  8. Efstathiou, A, Asteriou, C, Barbetakis, N, Miliaras, D, Kleontas, A, Karvelas, C,Primary pulmonary mucinous cystadenocarcinoma: a case report, Case Rep Med, 2011, 8, 562026(2011)
  9. Raza, SA, Alexakis, C, Creagh, M, Lawrence, DR, Wood, M,Primary pulmonary mucinous cystadenocarcinoma presenting as a complex bronchocele: a case report, J Med Case Rep, 3, 9, 8581(2009) https://doi.org/10.4076/1752-1947-3-8581
  10. Berger, KL, Nicholson, SA, Dehdashti, F, Siegel, BA,FDG PET evaluation of mucinous neoplasms: correlation of FDG uptake with histopathologic features, AJR Am J Roentgenol, 174, 10, 1005-1008(2000) https://doi.org/10.2214/ajr.174.4.1741005
  11. Rossi, G, Murer, B, Cavazza, A, Losi, L, Natali, P, Marchioni, A,Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression, Am J Surg Pathol, 28, 11, 442-452(2004) https://doi.org/10.1097/00000478-200404000-00003
  12. Wynveen, C, Behmaram, B, Haasler, G, Rao, N,Diverse histologic appearances in pulmonary mucinous cystic neoplasia: a case report, J Med Case Rep, 2, 12, 312(2008) https://doi.org/10.1186/1752-1947-2-312
  13. Maeda, R, Isowa, N, Onuma, H, Miura, H,Primary pulmonary mucinous (colloid) adenocarcinoma, Gen Thorac Cardiovasc Surg, 56, 13, 195-198(2008)
  14. Lee, HY, Lee, KS, Han, J, Kim, BT, Cho, YS, Shim, YM,Mucinous versus nonmucinous solitary pulmonary nodular bronchioloalveolar carcinoma: CT and FDG PET findings and pathologic comparisons, Lung Cancer, 65, 14, 170-175(2009) https://doi.org/10.1016/j.lungcan.2008.11.009
  15. Ishibashi, H, Moriya, T, Matsuda, Y, Sado, T, Hoshikawa, Y, Chida, M,Pulmonary mucinous cystadenocarcinoma: report of a case and review of the literature, Ann Thorac Surg, 76, 15, 1738-1740(2003) https://doi.org/10.1016/S0003-4975(03)00657-X
  16. Butnor, KJ, Sporn, TA, Dodd, LG,Fine needle aspiration cytology of mucinous cystadenocarcinoma of the lung: report of a case with radiographic and histologic correlation, Acta Cytol, 45, 16, 779-783(2001) https://doi.org/10.1159/000328305
  17. Tangthangtham, A, Chonmaitri, I, Tungsagunwattana, S, Charupatanapongse, U,Mucinous cystadenocarcinoma of the lung, J Med Assoc Thai, 81, 17, 794-798(1998)
  18. Gaeta, M, Blandino, A, Scribano, E, Ascenti, G, Minutoli, F, Pandolfo, I,Mucinous cystadenocarcinoma of the lung: CT-pathologic correlation in three cases, J Comput Assist Tomogr, 23, 18, 641-643(1999) https://doi.org/10.1097/00004728-199907000-00028
  19. Mann, GN, Wilczynski, SP, Sager, K, Grannis, FW,Recurrence of pulmonary mucinous cystic tumor of borderline malignancy, Ann Thorac Surg, 71, 19, 696-697(2001) https://doi.org/10.1016/S0003-4975(00)02174-3

Cited by

  1. A rare pleural mucinous cystadenocarcinoma mimicking loculated empyema initially: A case report vol.23, pp.4, 2013, https://doi.org/10.4103/0971-3026.125568
  2. Colloid Adenocarcinoma of the Lung: CT and PET/CT Findings in Seven Patients vol.211, pp.2, 2013, https://doi.org/10.2214/ajr.17.19273
  3. A diagnostic challenge: An incidental lung nodule in a 48-year-old nonsmoker vol.35, pp.3, 2013, https://doi.org/10.4103/lungindia.lungindia_212_17
  4. A lobulated mass in the left lower lobe: not what it seems vol.74, pp.5, 2013, https://doi.org/10.1136/thoraxjnl-2018-212520
  5. Pulmonary mucinous cystadenocarcinoma: an unusual presentation and literature review vol.13, pp.7, 2013, https://doi.org/10.1136/bcr-2020-235567