Korean Journal of Radiology

  • 제14권2호
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  • Pages.366-374
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  • 2013
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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Primary Endobronchial Marginal Zone B-Cell Lymphoma of Bronchus-Associated Lymphoid Tissue: CT Findings in 7 Patients

  • Yoon, Ra Gyoung (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Kim, Mi Young (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Song, Jae Woo (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Chae, Eun Jin (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Choi, Chang Min (Department of Pulmonary and Oncology Medicine, University of Ulsan College of Medicine) ;
  • Jang, SeJin (Department of Pathology, University of Ulsan College of Medicine)
  • 발행 : 2013.04.01
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: To investigate CT and $^{18}F$-flurodeoxyglucose ($^{18}F$-FDG) positron-emission tomography/CT findings of primary endobronchial marginal zone B-cell lymphoma of the bronchus-associated lymphoid tissue (BALT). Materials and Methods: From June 2006 through April 2012, seven patients (six female, one male; age range, 21-61 years; mean age, 49 years) were examined who were pathologically diagnosed with the primary endobronchial marginal zone B-cell lymphoma of BALT. We evaluated the locations and characteristics of the lesions on CT and $^{18}F$-FDG-PET/CT scans. The lesions were classified into the following three patterns: 1) solitary intraluminal nodule; 2) several tiny nodular protrusions; and 3) diffuse wall thickening. Results: A solitary intraluminal nodule was observed in four patients (57.1%), several tiny nodular protrusion in two patients (28.6%), and diffuse wall thickening in one patient (14.3%). The lesions were categorized into 3 major locations: confined to the trachea (n = 3), confined to the lobar bronchus (n = 2), and diffuse involvement of the trachea and both main bronchi (n = 2). All lesions demonstrated homogeneous iso-attenuation as compared with muscle on pre- and post-enhancement scans. Secondary findings in the lungs (n = 3; 42.9%) included postobstructive lobar atelectasis (n = 1), air trapping (n = 1), and pneumonia (n = 1). On $^{18}F$-FDG-PET/CT (n = 5), 4 lesions showed homogeneous uptake with maximum standardized uptake values (mSUV), ranging 2.3-5.7 (mean mSUV: 3.3). One lesion showed little FDG uptake. Conclusion: Primary endobronchial marginal zone B-cell lymphoma of the BALT manifests as three distinct patterns on CT, with the solitary intraluminal nodule presenting as the main pattern. Most lesions demonstrate homogeneous but weak FDG uptake on $^{18}F$-FDG-PET/CT.

키워드

참고문헌

  1. McGuinness, G, Scholes, JV, Jagirdar, JS, Lubat, E, Leitman, BS, Bhalla, M,Unusual lymphoproliferative disorders in nine adults with HIV or AIDS: CT and pathologic findings, Radiology, 197, 1, 59-65(1995) https://doi.org/10.1148/radiology.197.1.7568855
  2. Harris, NL, Jaffe, ES, Stein, H, Banks, PM, Chan, JK, Cleary, ML,A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group, Blood, 84, 2, 1361-1392(1994)
  3. Kinsely, BL, Mastey, LA, Mergo, PJ, Voytovich, MC, Zander, D, Almasri, NM,Pulmonary mucosa-associated lymphoid tissue lymphoma: CT and pathologic findings, AJR Am J Roentgenol, 172, 3, 1321-1326(1999) https://doi.org/10.2214/ajr.172.5.10227510
  4. Li, G, Hansmann, ML, Zwingers, T, Lennert, K,Primary lymphomas of the lung: morphological, immunohistochemical and clinical features, Histopathology, 16, 4, 519-531(1990) https://doi.org/10.1111/j.1365-2559.1990.tb01157.x
  5. Ahmed, S, Siddiqui, AK, Rai, KR,Low-grade B-cell bronchial associated lymphoid tissue (BALT) lymphoma, Cancer Invest, 20, 5, 1059-1068(2002) https://doi.org/10.1081/CNV-120005924
  6. Solomonov, A, Zuckerman, T, Goralnik, L, Ben-Arieh, Y, Rowe, JM, Yigla, M,Non-Hodgkin's lymphoma presenting as an endobronchial tumor: report of eight cases and literature review, Am J Hematol, 83, 6, 416-419(2008) https://doi.org/10.1002/ajh.21112
  7. Hoffmann, M, Kletter, K, Diemling, M, Becherer, A, Pfeffel, F, Petkov, V,Positron emission tomography with fluorine-18-2-fluoro-2-deoxy-D-glucose (F18-FDG) does not visualize extranodal B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT)-type, Ann Oncol, 10, 7, 1185-1189(1999) https://doi.org/10.1023/A:1008312726163
  8. Hoffmann, M, Kletter, K, Becherer, A, Jager, U, Chott, A, Raderer, M,18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) for staging and follow-up of marginal zone B-cell lymphoma, Oncology, 64, 8, 336-340(2003) https://doi.org/10.1159/000070290
  9. Beal, KP, Yeung, HW, Yahalom, J,FDG-PET scanning for detection and staging of extranodal marginal zone lymphomas of the MALT type: a report of 42 cases, Ann Oncol, 16, 9, 473-480(2005) https://doi.org/10.1093/annonc/mdi093
  10. Bae, YA, Lee, KS, Han, J, Ko, YH, Kim, BT, Chung, MJ,Marginal zone B-cell lymphoma of bronchus-associated lymphoid tissue: imaging findings in 21 patients, Chest, 133, 10, 433-440(2008) https://doi.org/10.1378/chest.07-1956
  11. Shin, CH, Paik, SH, Park, JS, Kim, HK, Park, SI, Cha, JG,Primary pulmonary T-cell lymphoma: a case report, Korean J Radiol, 11, 11, 234-238(2010) https://doi.org/10.3348/kjr.2010.11.2.234
  12. Brandtzaeg, P, Jahnsen, FL, Farstad, IN,Immune functions and immunopathology of the mucosa of the upper respiratory pathways, Acta Otolaryngol, 116, 12, 149-159(1996) https://doi.org/10.3109/00016489609137812
  13. Tirouvanziam, R, Khazaal, I, N'Sonde, V, Peyrat, MA, Lim, A, de Bentzmann, S,Ex vivo development of functional human lymph node and bronchus-associated lymphoid tissue, Blood, 99, 13, 2483-2489(2002) https://doi.org/10.1182/blood.V99.7.2483
  14. Anaya, JM, McGuff, HS, Banks, PM, Talal, N,Clinicopathological factors relating malignant lymphoma with Sjögren's syndrome, Semin Arthritis Rheum, 25, 14, 337-346(1996) https://doi.org/10.1016/S0049-0172(96)80019-9
  15. Tredaniel, J, Peillon, I, Ferme, C, Brice, P, Gisselbrecht, C, Hirsch, A,Endobronchial presentation of Hodgkin's disease: a report of nine cases and review of the literature, Eur Respir J, 7, 15, 1852-1855(1994) https://doi.org/10.1183/09031936.94.07101852
  16. Berkman, N, Lafair, J, Okon, E, Polliack, A,Obstructive solitary bronchial non-Hodgkin's lymphoma--a rare presentation of primary extranodal disease, Leuk Lymphoma, 8, 16, 405-407(1992) https://doi.org/10.3109/10428199209051021
  17. McRae, WM, Wong, CS, Jeffery, GM,Endobronchial non-Hodgkin's lymphoma, Respir Med, 92, 17, 975-977(1998) https://doi.org/10.1016/S0954-6111(98)90202-5
  18. Hashemi, SM, Heitbrink, MA, Jiwa, M, Boersma, WG,A patient with endobronchial BALT lymphoma successfully treated with radiotherapy, Respir Med, 101, 18, 2227-2229(2007) https://doi.org/10.1016/j.rmed.2006.11.028
  19. Erbaycu, AE, Karasu, I, Ozdemirkiran, FG, Yücel, N, Ozsöz, A, Bilgir, O,Endobronchial low-grade MALT lymphoma causing unilateral hypertranslucency, Monaldi Arch Chest Dis, 61, 19, 237-240(2004)
  20. Kang, JY, Park, HJ, Lee, KY, Lee, SY, Kim, SJ, Park, SH,Extranodal marginal zone lymphoma occurring along the trachea and central airway, Yonsei Med J, 49, 20, 860-863(2008) https://doi.org/10.3349/ymj.2008.49.5.860
  21. Nathwani, BN, Anderson, JR, Armitage, JO, Cavalli, F, Diebold, J, Drachenberg, MR,Marginal zone B-cell lymphoma: a clinical comparison of nodal and mucosa-associated lymphoid tissue types. Non-Hodgkin's Lymphoma Classification Project, J Clin Oncol, 17, 21, 2486-2492(1999) https://doi.org/10.1200/JCO.1999.17.8.2486

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