Korean Journal of Radiology

  • 제14권2호
  • /
  • Pages.287-293
  • /
  • 2013
  • /
  • 1229-6929(pISSN)
  • /
  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지
DOI QR코드

DOI QR Code

Accuracy of Preoperative MRI with Microscopy Coil in Evaluation of Primary Tumor Thickness of Malignant Melanoma of the Skin with Histopathologic Correlation

  • Kang, Yusuhn (Department of Radiology, Seoul National University College of Medicine) ;
  • Choi, Jung-Ah (Department of Radiology, Seoul National University College of Medicine) ;
  • Chung, Jin-Haeng (Department of Pathology, Seoul National University Bundang Hospital) ;
  • Hong, Sung Hwan (Department of Radiology, Seoul National University College of Medicine) ;
  • Kang, Heung Sik (Department of Radiology, Seoul National University College of Medicine)
  • 발행 : 2013.04.01
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: The purpose of this study was to evaluate the accuracy of a preoperative MRI with microscopy coils in determining the primary tumor thickness of malignant melanoma with histopathologic correlation. Materials and Methods: Eleven patients with histopathologically confirmed malignant melanoma were included in this study. MR images of the tumors were obtained with a 47-mm microscopy coil on 1.5T MR scanners and were evaluated by two radiologists, who assessed the thickness of the primary tumor on T2-weighted images (T2WI) and gadolinium-enhanced T1-weighted images with fat suppression (Gd-T1WI) and compared the results with the histopathologic findings as the reference standard. Correlations between tumor thickness on MRI and histopathologic examination were assessed using concordance correlation coefficients (CCCs). Inter- and intraobserver variabilities of tumor measurements were also assessed by intraclass correlation coefficient (ICC). Results: Among the 11 cases included in the study, 10 cases from the same number of patients were managed with surgical excision and one case was confirmed with punch biopsy. The primary tumor thickness measured on T2WI showed better correlation with histopathologic results, as compared with measurements taken on Gd-T1WI: the CCC of measurements on T2WI ranged from 0.64 to 0.78, indicating a substantial agreement, whereas the CCC of measurements on Gd-T1WI ranged from 0.50 to 0.61, indicating a moderate to substantial agreement. Inter- and intraobserver agreements of readers 1 and 2 were excellent for both T2WI and Gd-T1WI, with ICC ranging from 0.86 to 0.99. Conclusion: MR imaging with microscopy coils may be an accurate technique in the preoperative assessment of tumor thickness in malignant melanoma, especially on T2-weighted images.

키워드

참고문헌

  1. Rajeswari, MR, Jain, A, Sharma, A, Singh, D, Jagannathan, NR, Sharma, U,Evaluation of skin tumors by magnetic resonance imaging, Lab Invest, 83, 1, 1279-1283(2003) https://doi.org/10.1097/01.LAB.0000088767.45565.27
  2. Kim, HJ, Lee, SH, Kang, CH, Ryu, JA, Shin, MJ, Cho, KJ,Evaluation of the chondromalacia patella using a microscopy coil: comparison of the two-dimensional fast spin echo techniques and the three-dimensional fast field echo techniques, Korean J Radiol, 12, 2, 78-88(2011) https://doi.org/10.3348/kjr.2011.12.1.78
  3. Georgouli, T, James, T, Tanner, S, Shelley, D, Nelson, M, Chang, B,High-resolution microscopy coil MR-Eye, Eye (Lond), 22, 3, 994-996(2008) https://doi.org/10.1038/sj.eye.6702755
  4. Lee, IS, Choi, JA, Oh, JH, Chung, JH, Jeong, HS, Hong, SH,Microscopy coil for preoperative MRI of small soft-tissue masses of the hand and foot: comparison with conventional surface coil, AJR Am J Roentgenol, 191, 4, W256-W263(2008) https://doi.org/10.2214/AJR.07.3011
  5. Maderwald, S, Ladd, SC, Ladd, ME, Stock, F, Paul, T, Liffers, A,High SNR, Microscopic Imaging of Skin Lesions, Proc Intl Soc Mag Reson Med, 14, 5, 1737(2006)
  6. Maurer, J, Knollmann, FD, Schlums, D, Garbe, C, Vogl, TJ, Bier, J,Role of high-resolution magnetic resonance imaging for differentiating melanin-containing skin tumors, Invest Radiol, 30, 6, 638-643(1995) https://doi.org/10.1097/00004424-199511000-00003
  7. Pennasilico, GM, Arcuri, PP, Laschena, F, Potenza, C, Ruatti, P, Bono, R,Magnetic resonance imaging in the diagnosis of melanoma: in vivo preliminary studies with dynamic contrast-enhanced subtraction, Melanoma Res, 12, 7, 365-371(2002) https://doi.org/10.1097/00008390-200208000-00009
  8. Balch, CM, Murad, TM, Soong, SJ, Ingalls, AL, Halpern, NB, Maddox, WA,A multifactorial analysis of melanoma: prognostic histopathological features comparing Clark's and Breslow's staging methods, Ann Surg, 188, 8, 732-742(1978) https://doi.org/10.1097/00000658-197812000-00004
  9. Ivan, D, Prieto, VG,An update on reporting histopathologic prognostic factors in melanoma, Arch Pathol Lab Med, 135, 9, 825-829(2011)
  10. Busing, KA, Kilian, AK, Schaible, T, Debus, A, Weiss, C, Neff, KW,Reliability and validity of MR image lung volume measurement in fetuses with congenital diaphragmatic hernia and in vitro lung models, Radiology, 246, 10, 553-561(2008) https://doi.org/10.1148/radiol.2462062166
  11. Kim, SY, Lee, SS, Byun, JH, Park, SH, Kim, JK, Park, B,Malignant hepatic tumors: short-term reproducibility of apparent diffusion coefficients with breath-hold and respiratory-triggered diffusion-weighted MR imaging, Radiology, 255, 11, 815-823(2010) https://doi.org/10.1148/radiol.10091706
  12. Mazaheri, Y, Hricak, H, Fine, SW, Akin, O, Shukla-Dave, A, Ishill, NM,Prostate tumor volume measurement with combined T2-weighted imaging and diffusion-weighted MR: correlation with pathologic tumor volume, Radiology, 252, 12, 449-457(2009) https://doi.org/10.1148/radiol.2523081423
  13. Lin, LI,A concordance correlation coefficient to evaluate reproducibility, Biometrics, 45, 13, 255-268(1989) https://doi.org/10.2307/2532051
  14. Landis, JR, Koch, GG,The measurement of observer agreement for categorical data, Biometrics, 33, 14, 159-174(1977) https://doi.org/10.2307/2529310
  15. Balch, CM, Gershenwald, JE, Soong, SJ, Thompson, JF, Atkins, MB, Byrd, DR,Final version of 2009 AJCC melanoma staging and classification, J Clin Oncol, 27, 15, 6199-6206(2009) https://doi.org/10.1200/JCO.2009.23.4799
  16. Veronesi, U, Cascinelli, N,Narrow excision (1-cm margin). A safe procedure for thin cutaneous melanoma, Arch Surg, 126, 16, 438-441(1991) https://doi.org/10.1001/archsurg.1991.01410280036004
  17. Veronesi, U, Cascinelli, N, Adamus, J, Balch, C, Bandiera, D, Barchuk, A,Thin stage I primary cutaneous malignant melanoma. Comparison of excision with margins of 1 or 3 cm, N Engl J Med, 318, 17, 1159-1162(1988) https://doi.org/10.1056/NEJM198805053181804
  18. Krug, B, Kugel, H, Schulze, HJ, Krahe, T, Gieseke, J, Lackner, K,High-resolution MR imaging of the cutis and subcutis. Histological correlation, Acta Radiol, 39, 18, 547-553(1998)
  19. Gufler, H, Franke, FE, Rau, WS,High-resolution MRI of basal cell carcinomas of the face using a microscopy coil, AJR Am J Roentgenol, 188, 19, W480-W484(2007) https://doi.org/10.2214/AJR.05.0799
  20. Kalli, S, Freer, PE, Rafferty, EA,Lesions of the skin and superficial tissue at breast MR imaging, Radiographics, 30, 20, 1891-1913(2010) https://doi.org/10.1148/rg.307105064

피인용 문헌

  1. High-Resolution Microscopy-Coil MR Imaging of Skin Tumors: Techniques and Novel Clinical Applications vol.35, pp.4, 2013, https://doi.org/10.1148/rg.2015140142
  2. Selection and Reporting of Statistical Methods to Assess Reliability of a Diagnostic Test: Conformity to Recommended Methods in a Peer-Reviewed Journal vol.18, pp.6, 2017, https://doi.org/10.3348/kjr.2017.18.6.888
  3. The value of preoperative high‐resolution MRI with microscopy coil for facial nonmelanoma skin cancers vol.27, pp.1, 2013, https://doi.org/10.1111/srt.12909
  4. Clinical value of high‐resolution dynamic contrast‐enhanced (DCE) MRI in diagnosis of cutaneous squamous cell carcinoma vol.27, pp.4, 2013, https://doi.org/10.1111/srt.12978