The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Differential Diagnosis of Secondary Glomerulonephritis

이차성 사구체신염의 감별진단

  • Kim, Min Jee (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Soo Wan (Department of Internal Medicine, Chonnam National University Medical School)
  • 김민지 (전남대학교 의과대학 내과학교실) ;
  • 김수완 (전남대학교 의과대학 내과학교실)
  • Published : 2013.01.01
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Abstract

Early diagnosis of glomerulonephritis is important in initiating appropriate treatment and controlling chronic glomerular injury that may eventually lead to end-stage renal disease. Although many patients with glomerular disease have only renal involvement, systemic presentations are not uncommon, as frequently resulted from an underlying systemic disease or a factor such as infections, drugs, or metabolic diseases. The presence of an underlying secondary reason should be investigated in each glomerular disease independent of its histopathologic type. Laboratory tests may include C3, C4, ANA, dsDNA, antineutrophil cytoplasmic antibody titers, a streptozyme test, HBV and HCV serologies, and in some cases, blood cultures, anti-glomerular basement membrane antibodies, and cryoglobulins. Although serologic tests may be helpful in establishing a diagnosis in some patients, a renal biopsy is usually performed even if serologic testing is positive. In addition, serologic test may assist in interpretation of the renal pathology.

Keywords

References

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