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A Case of Pseudohyperphosphatemia in a Patient with Multiple Myeloma

가성고인산혈증을 보인 다발골수종 1예

  • Lee, Sun Ah (Department of Internal Medicine, Daegu Fatima Hospital) ;
  • Lee, Jung Lim (Department of Internal Medicine, Daegu Fatima Hospital) ;
  • Park, Kun Woo (Department of Internal Medicine, Daegu Fatima Hospital) ;
  • Kim, Hyeong Seok (Department of Internal Medicine, Daegu Fatima Hospital) ;
  • Bae, Soo Hyun (Department of Internal Medicine, Daegu Fatima Hospital) ;
  • Chang, Soon Hee (Department of Laboratory Medicine, Daegu Fatima Hospital)
  • 이선아 (대구파티마병원 내과) ;
  • 이정림 (대구파티마병원 내과) ;
  • 박건우 (대구파티마병원 내과) ;
  • 김형석 (대구파티마병원 내과) ;
  • 배수현 (대구파티마병원 내과) ;
  • 장순희 (대구파티마병원 진단검사의학과)
  • Published : 2013.01.01

Abstract

Hyperphosphatemia develops when there is impaired renal phosphate excretion or massive extracellular fluid phosphate load. For example, renal insufficiency, hypoparathyroidism, exogenous phosphate administration, and extensive cellular injury induce a hyperphosphatemic state. In patients with multiple myeloma, renal insufficiency occurs as a result of hypercalcemia, light chain tubulopathy, urate nephropathy or infection, and hyperphosphatemia usually results from renal failure. We report here a case of a patient with multiple myeloma who had an elevated serum phosphate level measured by the phosphomolybdate UV method without significant renal insufficiency and was finally diagnosed with pseudohyperphosphatemia.

저자들은 IgG, kappa 다발골수종 환자에서 설명되지 않는 고인산혈증이 있어 가성고인산혈증을 의심하고 sulfosalicylic acid를 이용하여 환자의 혈청에서 단백질을 제거 후 다시 인을 측정하여 정상 인 수치를 보인 1예를 경험하였으므로 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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