The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Treatment of Primary Glomerulonephritis

일차성 사구체신염의 치료

  • Ihm, Chun-Gyoo (Department of Internal Medicine, Kyung Hee University College of Medicine)
  • 임천규 (경희대학교 의과대학 내과학교실)
  • Published : 2013.01.01
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Abstract

Much progress has been made in the elucidation of potential pathogenetic mechanisms of glomerulonephritis such as anti-PLA2R autoantibody in membranous nephropathy and under-galactosylated IgA1 in IgA nephropathy as well as in the fields of treatment. This knowledge is, hopefully in the future, being applied in the development of the creation of rational therapeutic approaches. Current treatment strategies for glomerular diseases recommended by many clinical studies include high-dose glucocorticoids, calcineurin inhibitors, cyclophosphamide, mycophenolate mofetil, and rituximab. Although these therapies have been effective in treating immune-mediated glomerular diseases, they all have potentially serious side effects.

Keywords

References

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