Abstract
Interstitial lung diseases are diagnosed based on clinical, radiological, and histopathological findings. There are various kinds of interstitial lung diseases involving both the interstitium and bronchioles. Bronchiolitis interstitial pneumonitis (BIP) was recently reported as an independent disease cluster combined with both interstitial pneumonitis and bronchiolitis, which is not classified in a specific category of idiopathic interstitial pneumonia (IIP) by the present classification. In this case report, we introduce a recently experienced patient with BIP. A 68-year-old female visited our hospital with aggravated dyspnea for the past 2 months. Her chest computed tomography scan compared to 6 months ago showed increased reticulonodular lesion and ground glass opacities, suggesting interstitial lung disease. A video-assisted thoracoscopic biopsy from a right lower lobe wedge resection resulted in the diagnosis of BIP. Clinical symptoms, pulmonary lesions, and pulmonary function test results remained stable for 1.5 years after oral glucocorticoid and immunosuppressive therapy.
현 분류 체계로는 특정 분류에 속하지 않으면서, 세기관지와 간질을 동시에 침범하는 간질성 폐질환 환자에서 폐생검을 통하여 BIP로 진단하였고, 면역억제제 사용 후 호전 및 안정적인 경과를 보이는 증례를 경험하여 이를 보고하는 바이다.