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A Case of a Deep Neck Space Candidial Abscess in an Immunocompetent Woman

정상 면역 여성에서 발생한 심경부의 칸디다 농양 1예

  • Chang, Hyo Jeong (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Bae, Hyung Gy (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Yu, Sung In (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Lee, Hyuk Pyo (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Choi, Soo Jeon (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Kim, Hyun Jung (Department of Pathology, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Choi, Sang Bong (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine)
  • 장효정 (인제대학교 의과대학 상계백병원 내과) ;
  • 배형기 (인제대학교 의과대학 상계백병원 내과) ;
  • 유성인 (인제대학교 의과대학 상계백병원 내과) ;
  • 이혁표 (인제대학교 의과대학 상계백병원 내과) ;
  • 최수전 (인제대학교 의과대학 상계백병원 내과) ;
  • 김현정 (인제대학교 의과대학 상계백병원 병리학과) ;
  • 최상봉 (인제대학교 의과대학 상계백병원 내과)
  • Published : 2013.01.01

Abstract

Deep neck space infections usually arise from infectious conditions of the upper aerodigestive tract. Candida albicans is a normal commensal of humans but usually causes invasive infections in immunocompromised patients. We report an immunocompetent 70-year-old woman with a Candida abscess in the deep neck space. She did not have dental or oropharyngeal disease, medication use, or medical illnesses that could cause an immunocompromised condition, except stable chronic hepatitis C. She was admitted to the hospital with fever, shortness of breath, a drowsy consciousness, and swallowing difficulty. Despite empirical antibiotic therapy, her signs and symptoms did not improve. A deep neck space abscess in the retropharyngeal space was revealed by computed tomography (CT). An abscess culture yielded C. albicans. She was treated with an antifungal agent rather then antibiotics. After 5 weeks of antifungal agent treatment and external drainage, follow-up CT scans showed substantial improvement in the abscess.

심경부감염의 원인 질환으로는 치아 감염증과 구강인두감염증이 흔한데 원인이 밝혀지지 않는 경우도 많다. 칸디다알비칸스는 칸디다 중 가장 흔한 병원균인데 주로 면역 약화자에게 감염증을 일으킨다. 저자들은 정상면역기능을 가진 70세 여성에서 발생한 심경부 칸디다 농양을 경험하여 보고하는 바이다. 환자는 안정적인 C형간염 이외에 면역억제를 일으킬 만한 특이 질환이나 약물 복용력이 없었고 구강이나 인두에 병변도 없었다. 내원 5일 전부터 발열과 호흡곤란, 의식장애가 발생하였고 항생제 투여에도 큰 호전 없이 연하장애도 동반되었다. 컴퓨터단층촬영에서 인두 뒤 공간에 농양이 발견되었고 세침흡인으로 배양검사를 시행한 결과 칸디다 알비칸스가 동정되었다. 수술적 배액을 시행하고 항생제를 항진균제로 교체하여 5주간 투여 뒤 컴퓨터단층촬영에서 병변이 모두 소실되어 퇴원하였다.

Keywords

References

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