The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Vaccines against Coccidioides

  • Yoon, Hee Jung (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital) ;
  • Clemons, Karl V. (California Institute for Medical Research, Stanford University School of Medicine)
  • Published : 2013.07.01
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Abstract

Vaccines against fungal diseases are gaining attention because of their growing impact on modern medicine. Development of these vaccines should incorporate immunological tools that integrate with or replace chemotherapy to minimize antibiotic use and consequent resistance. In this review, we evaluate the current developmental status of fungal vaccines against coccidioidomycosis. There is a need for a vaccine that sufficiently prevents disease, without eradicating the fungus, by neutralizing adhesions and enzymes or other low penetrance virulence traits.

Keywords

References

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