The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma

  • Kim, Mi Ra (Kim Yong Ki Internal Medicine Clinic) ;
  • Kim, Sang Soo (Department of Internal Medicine, Pusan National University Hospital) ;
  • Huh, Jung Eun (HanSeo Hospital) ;
  • Lee, Byung Joo (Department of Otolaryngology, Pusan National University Hospital) ;
  • Lee, Jin Choon (Department of Otolaryngology, Pusan National University Hospital) ;
  • Jeon, Yun Kyung (Department of Internal Medicine, Pusan National University Hospital) ;
  • Kim, Bo Hyun (Department of Internal Medicine, Pusan National University Hospital) ;
  • Kim, Seong Jang (BioMedical Research Institute, Pusan National University Hospital) ;
  • Wang, Soo Geun (Department of Otolaryngology, Pusan National University Hospital) ;
  • Kim, Yong Ki (Kim Yong Ki Internal Medicine Clinic) ;
  • Kim, In Joo (Department of Internal Medicine, Pusan National University Hospital)
  • Published : 2013.01.01
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Abstract

Background/Aims: Obesity is correlated with numerous diseases, including thyroid cancer, but the clinical significance of obesity with regard to the clinical characteristics of thyroid cancer remains unclear. Neck circumference is an index of upper-body adipose tissue distribution. Methods: In total, 401 patients with papillary thyroid carcinoma (PTC) measuring ${\leq}$ 2cm were included. Neck circumference was measured horizontally at the level just below the thyroid cartilage on preoperative neck computed tomographic images. Results: Neck circumference correlated significantly with tumor size in men (p = 0.001) but not in women (p = 0.930). Body mass index (BMI) did not significantly correlate with tumor size in either sex. Neck circumference was significantly larger in men with lateral lymph node (LN) metastasis than in those without (p = 0.004). Neck circumference and BMI did not differ significantly in women according to other factors such as tumor size, multifocality, extrathyroid extension, and LN metastasis. Tumor size and the prevalence of lateral LN metastasis in men tended to increase in the middle/large neck circumference subgroup compared with those in the low neck circumference subgroup. Multivariate logistic regression analysis revealed that neck circumference (p = 0.009) was a predictor for the presence of lateral LN metastasis in men. BMI was not a predictive factor for lateral LN involvement in either sex. Conclusions: Neck circumference, an indicator of central or visceral obesity but not BMI, may be associated with some prognostic factors in men with small PTC.

Keywords

References

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